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Results for tyrosine kinase. Search took 0.32 seconds.
Brain Enzyme Regulates Appetite and Weight Gain
in The Biotech Weblog, on December 14, 2008
... Scientists have determined that an enzyme in the brain called p70 S6 Kinase 1 or S6K may play a role in preventing weight gain and obesity. The researchers injected rats with special viruses t...
Cancer Drug Gleevec May Treat Type 1 Diabetes
in Daily Diabetic, on November 19, 2008
...tes Center at the University of California, San Francisco:
"Although targeted to the Bcr-Abl kinase, Gleevec has been shown to affect related kinases including platelet-derived growth factor po...
Nexavar® (sorafenib), FDA-Approved for Inoperable Hepatocellular Carcinoma
in Straightfromthedoc, on November 21, 2007
..., Inc. (Emeryville, California) - Nexavar® (sorafenib) - is a type of anticancer drug called a kinase inhibitor that interferes with molecules that are thought to be involved in chemical messages s...
FTY720 May Treat Imatinib (Gleevec)- Resistant Leukemia
in The Biotech Weblog, on August 28, 2007
... leukemia and some cases of acute lymphocytic leukemia. These are fatal leukemias against which Abl kinase inhibitors such as imatinib (Gleevec) fail to induce a long-term response. FTY720 activates p...
FDA Approved New Kidney Cancer Drug: Torisel™ (temsirolimus) by Wyeth
in Straightfromthedoc, on June 1, 2007
...eted cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase [a key protein in cells that regulates cell proliferation, cell growth and cell survival] is expected...
Scientific Progress Against Diabetic Retinopathy
in Daily Diabetic, on April 26, 2007
...een found to slow the progression of retinopathy by inhibiting an enzyme in the body called protein kinase C beta (PKC beta). PKC is believed to contribute to the blood vessel damage that leads to the...
TYKERB®: GlaxoSmithKline's Breast Cancer Drug, Approved by the FDA
in The Biotech Weblog, on March 16, 2007
...s or disease mechanisms prevalent in cancer - it inhibits two validated targets in oncology, the kinase components of the EGFR (ErbB1) and HER2 (ErbB2) receptors, commonly associated with cancer cell ...
Enzyme Deficiency May Cause Diabetes In Newborns
in Daily Diabetic, on December 9, 2006
...anent diabetes in newborn babies may be a deficiency in the enzyme Pancreatic Endoplasmic Reticulum Kinase (PERK) during a critical period of development before birth, according to a new hypothesis pu...
Rho Kinase Inhibitors May Treat Certain Gastrointestinal Disorders
in The Biotech Weblog, on July 19, 2006
...
An enzyme called Rho kinase has been shown to play a role in maintaining the tone of the internal anal sphincter (IAS). When the IAS tone is too high, the anal sphincter can be hypertensi...
Natural Protein, Protects Against Obesity
in Straightfromthedoc, on April 21, 2006
... the effects of obesity.
The team found that CNTF activates an enzyme called skeletal muscle AMP kinase, which in turns boosts the body's ability to metabolize fat and sugar. CNTF activates pat...
animal study in chromium supplements: hope for diabetes
in Straightfromthedoc, on February 8, 2006
...in-stimulated phosphorylation of insulin receptor substrate (IRS)-1 and phosphatidylinositol (PI)-3 kinase activity in skeletal muscle compared with obese controls," wrote the researchers.
The ...
cancer cells' defense mechanism unlocked
in Straightfromthedoc, on February 6, 2006
...e found a chink in the tumor's armor .
"We have found a gene called focal adhesion kinase which is produced at very high levels in human tumors, and our work has shown this makes the ...
omega-6 fats hasten growth of prostate tumor
in Straightfromthedoc, on February 6, 2006
...ing on those genes, and found that omega-6 fatty acids actually turn on a signal pathway called PI3-kinase that is known to be a key player in cancer," she adds.
Omega 6 fatty acids are one o...
New Target For Anti-Inflammatory Compounds
in The Biotech Weblog, on December 6, 2005
...of ceramide conducted by researchers fom the Virginia Commonwealth University suggest that ceramide kinase (CERK) could be a novel target for the development of a new generation of anti-inflammato...
Soluble Endoglin and Soluble Fms-like Tyrosine Kinase 1 (sFlt1): Proteins in Pregnant Woman's Blood That Predict Development of Preeclampsia
in Straightfromthedoc, on September 19, 2006
...ne.
Levels rose still further after the onset of gestational hypertension.
2) soluble fms-like tyrosine kinase 1 (sFlt1)
The increase in sFlt1 was accompanied by reduced levels of a substance,... ...els rose still further after the onset of gestational hypertension.
2) soluble fms-like tyrosine kinase 1 (sFlt1)
The increase in sFlt1 was accompanied by reduced levels of a substance, placenta...
Studying Tyrosine Kinase Src and Cancer Drug Discovery
in The Biotech Weblog, on March 10, 2006
... Researchers from John Hopkins identified a novel method to study tyrosine kinase Src , an important protein implicated in cancer. An inactivated, mutated version of the Src protein, which could ag... ... Researchers from John Hopkins identified a novel method to study tyrosine kinase Src , an important protein implicated in cancer. An inactivated, mutated version of the Src protein, which could ag...
Cephalon Acquires Rights To Psoriasis Drug Candidate
in The Biotech Weblog, on December 12, 2005
...nhibiting production of keratinocytes, the major cell type making up the epidermis, by blocking the tyrosine kinase receptor (TrkA) of nerve growth factors.
Efficacy studies in different models and s... ... production of keratinocytes, the major cell type making up the epidermis, by blocking the tyrosine kinase receptor (TrkA) of nerve growth factors.
Efficacy studies in different models and safety/pha...