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Researchers Find Nanoparticles Can Damage Nearby DNA
in Nanotechbuzz, on November 7, 2009
© ynse
Researchers at the University of Bristol have found that nanoparticles being used to fight cancer can damage the DNA in nearby cells. Their research has been published in the current issue of the journal Nature Nanotechnology .
"In the experiment, scientists from the Un...
Cell phones and brain cancer
in Sox First, on October 26, 2009
...ganization (WHO) is set to publish evidence that heavy users face a higher risk of developing brain tumors later in life. This is no small study. It was conducted in 13 countries and some 2800 peopl...
Radiation Therapy at Childhood Increases Risk of Future Breast Cancer
in Well Woman Blog, on July 29, 2009
...ents included a high dose of radiation to the ovaries, women's risk of developing future breast tumors was "sharply reduced".
Radiation therapy is normally conducted for the followin...
Lung Cancer Susceptibility Gene Identified
in The Biotech Weblog, on May 2, 2009
...sing a genetically altered mouse model, researchers determined that when RGS17 was suppressed, lung tumors shrank, proving the gene was involved in cancer development and must be present for cancer gr...
Walnuts May Help Fight Breast Cancer
in The Biotech Weblog, on April 27, 2009
... diet with no walnuts. They discovered that the walnut munchers were less likely to develop breast tumors, and if they did, their tumors were smaller and affected fewer mammary glands. The mice, which...
Cancer Research UK Announces Nanotech Breakthrough
in Nanotechbuzz, on March 13, 2009
...hool of Pharmacy in London, said it was the first time that nanoparticles had been shown to target tumors in such a selective way," according to Reuters .
"Once inside the cell, the gene...
MIT Student Wins Prize for Nanomedicine Research
in Nanotechbuzz, on March 7, 2009
...t Prize for "developing a technique that utilizes nanosize gold particles to target malignant tumors and kill cancer cells but spares healthy tissue," according to Scientific American'...
An Apple A Day Keeps The Breast Cancer-Doctor Away
in Well Woman Blog, on February 19, 2009
...he recent papers reported that fresh apple extracts significantly inhibited the size of mammary tumors in rats - and the more extracts they were given, the greater the inhibition.
According to Dr...
Pathwork Launches New Version of Tissue of Origin Test
in Straightfromthedoc, on January 13, 2009
...availability of a new version of the Pathwork Tissue of Origin Test, which aids in the diagnosis of tumors with uncertain origins. The new version uses formalin-fixed, paraffin-embedded (FFPE) tissue ...
Osteoporosis Drug Zometa Shrinks Breast Cancer Tumors
in Straightfromthedoc, on December 12, 2008
...
The osteoporosis drug Zometa (a product of Novartis AG) has been found to shrink breast cancer tumors better than chemotherapy alone .
Zometa is currently used to help prevent the bone loss ass...
UK Validation Study Initiated on Pathwork Tissue of Origin Test
in The Biotech Weblog, on December 10, 2008
...
The proof-of-concept study with the test, which helps diagnose the origin of difficult-to-identify tumors, will validate it for use in their institution, and give them information to help them determ...
Esophageal Cancer Awareness
in Straightfromthedoc, on November 11, 2008
...stic is due largely to the fact that by the time the majority of cases are diagnosed, the cancerous tumors have grown to the point of inoperability. Raising patient awareness about potential condition...
Jasmine Flower-Derived Substance, Potential New Anti-Cancer?
in The Biotech Weblog, on August 26, 2008
...own as jasmonate (or methyl jasmonate) has been found to be responsive to blood cancers and solid tumors as demonstrated in preclinical studies and early first-in-man studies.
According to Prof. Fl...
Anti-Cancer Drug Candidate Largazole
in The Biotech Weblog, on August 9, 2008
.... Overactivity of certain HDACs has been associated with several cancers such as prostate and colon tumors, and inhibiting HDACs can activate tumor-suppressor genes that have been silenced in these ca...
Stopping the Spread of Cancer by Using Nanoparticle-Mediated Drug Delivery
in Nanotechbuzz, on July 22, 2008
...ype of novel targeted approach, scientists have been able to stop the spread of cancer cells. Since tumors rely on blood vessels to survive, the effective use of nanoparticles to deliver drugs may rev...
Synthetic Flavanol May Prevent or Treat Cancer
in The Biotech Weblog, on June 16, 2008
...n of procyanidins, a class of flavanols, slowed the growth and accelerated the destruction of human tumors in laboratory studies, and may thus have potentials for cancer chemoprevention or even treat...
Nanoworms and Malignant Tumors
in Nanotechbuzz, on May 24, 2008
...t brain tumor called glioblastoma . This is really unfortunate news because malignant brain tumors are very difficult to treat. There are no cures or really effective remedies. However, nanote...
Using Skin Flaps to Deliver Anti-Cancer Drugs
in The Biotech Weblog, on May 15, 2008
...structive surgery , doctors report of using skin flaps to deliver anti-cancer proteins on rat tumors, resulting in a 79 percent reduction in tumor volume.
"This new technique may allow us ...
Good Cause at Full Tilt
in Internet Poker, on April 2, 2008
...ney for a pair of nephews of players from http://theroundersroom.com/forums/ who are fighting brain tumors. In addition to running 10K, they're raising money via a private tournament at Full Tilt....
Pregnancy and Dental Woes
in Next Nine Months, on March 25, 2008
...would be bleeding when brushing teeth. Another less common condition is the formation of pregnancy tumors in the gums . Don't worry, they aren't cancerous. They are just extreme inflammatory ...
Stem Cell Therapy Against Diabetes: A Breakthrough!
in Daily Diabetic, on February 21, 2008
...ersity of Miami, who was not involved in the research.
Still, a small number of the mice developed tumors, and some experts said the cells might not be well-characterized enough for use in people. In...
Study Warns of Cancer Risk with Heavy Mobile Phone Use
in The Wireless Weblog, on February 19, 2008
A study published in the American Journal of Epidemiology reports that Israeli mobile phone users "who had used the phone against one side of the head for several hours a day were 50% more likely to have developed a salivary gland tumor ," BBC News reports .
"The study also...
Researchers Identify Cause of Neurofibromatosis Type1
in The Biotech Weblog, on February 18, 2008
...ype1 , a genetic disease characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the skin, brain, and other parts of the body.
Researchers have long wondered...
'Laziness' of Regulatory T-cells, Lead to Type 1 Diabetes
in Daily Diabetic, on January 18, 2008
...mmatory responses. They suppress and regulate the function of various immune responses to microbes, tumors, allergens and transplants."
The said study was conducted on non-obese diabetic (NOD) ...
Sirolimus (Rapamune) May Treat Genetic Disease Tuberous Sclerosis
in The Biotech Weblog, on January 14, 2008
... , may have potentials in treating tuberous sclerosis , a rare genetic disease that causes benign tumors to grow in the brain and on other vital organs such as the kidneys, heart, eyes, lungs, and s...
Novel Protein, Potential Drug Target for Treatment-Resistant Prostate Cancer
in Straightfromthedoc, on December 31, 2007
...eprivation therapy. The researchers found Stat5 was active in 95 percent of these hormone resistant tumors, meaning it was more likely to be active if the patient had been treated with hormone depriva...
Taxol+Avastin Greatly Slowed Progression of Breast Cancer
in Straightfromthedoc, on December 30, 2007
..."
A human monoclonal antibody that acts to reduce the development of blood vessels that feed tumors - Avastin - a product of Genentech , has already been approved by the FDA for the treatm...
Lapatinib (Tykerb) -Capecitabine (Xeloda) Combo Shrinks Breast Cancer Metastases in the Brain
in Straightfromthedoc, on December 18, 2007
...geted therapy - and capecitabine - a chemotherapy agent - has been found to shrink metastatic brain tumors by at least 50 percent in one-fifth of patients with aggressive HER2-positive breast cancer.
...
Lost Dopamine Cells Replacement: Promising Therapeutic Strategy for Parkinson's
in Straightfromthedoc, on December 5, 2007
... recovery when transplanted into mice with PD-like disease.
Importantly, the mice did not develop tumors, a potential risk that has precluded the clinical development of embryonic stem cells as a so...
Cryoablation, Still Showing Good Results Against Kidney Cancer
in Straightfromthedoc, on November 26, 2007
...
Now a review of 62 Mayo Clinic patients who underwent cryoablation to treat cancerous kidney tumors shows that the patients are cancer free for up to two and a half years after having had the p...
REVLIMID® (lenalidomide)-Dexamethasone Combo, Effective in Multiple Myeloma
in Straightfromthedoc, on November 23, 2007
...em by stopping angiogenesis - the growth of blood vessels that penetrate into and feed cancerous tumors causing them to proliferate.
On the other hand, dexamethasone is a corticosteroid that is si...
Nexavar® (sorafenib), FDA-Approved for Inoperable Hepatocellular Carcinoma
in Straightfromthedoc, on November 21, 2007
...lved in chemical messages sent within cancer cells, in the formation of blood vessels that supply tumors, and in cell death.
Find more details from the FDA News .
[Photo Credit: EurekAlert ]...
Remotely-Controlled Nanoparticles Can Deliver Drugs Direct Into Tumors
in Straightfromthedoc, on November 21, 2007
...trolled nanoparticles - which when pulsed with an electromagnetic field, release drugs to attack tumors, have been developed by Massachusetts Institute of Technology (MIT). scientists.
Such ...
GPRC5A: Lung Cancer Tumor-Suppressor Gene, Identified in Mouse Models
in Straightfromthedoc, on November 16, 2007
...hat is under-expressed in human lung cancer cells - GPRC5A - which was found to suppress lung tumors in mouse models.
The study found that mice with both of their GPRC5A genes suppressed devel...
People with Allergies, Less Likely to Develop Glioma
in Allergies, on November 8, 2007
...ogy .
Their data indicate that people with allergies have a lower risk of developing glioma , tumors that develop often in the brain, spinal cord and optic nerves.
Doctors found people w...
High Glucose Level is Associated to Colorectal Cancer
in Daily Diabetic, on November 5, 2007
... have been found by a new study to increase the risk of developing recurrent colorectal adenomas or tumors.
According to Andrew Flood, PhD, of the University of Minnesota and lead author of the study...
Biodegradable Nanoparticles For Delivery of Cancer Drugs
in The Biotech Weblog, on October 25, 2007
....
Preliminary experiments have shown that the nanoparticles accumulated to a larger extent in mice tumors in and the encapsulated drugs were only released upon after the lactic acid groups in the pol...
Drinking Milk May Prevent Cancer Metastasis To Bones
in Straightfromthedoc, on October 7, 2007
...ng therapy.
About 70 percent of patients who develop advanced breast cancer will have secondary tumors in the bone. The spread of cancer to bones leads to cellular processes that physically brea...
Genetic Profiling Lung Tumors To Determine Best Chemotherapy Options
in The Biotech Weblog, on October 1, 2007
...Researchers are exploring the use of genetic profiling in lung tumors to to predict the tumors' likely response to therapy and determine the best treatment strategy for lung cancers.
Research...
Pfizer's Axitinib: New Promising Experimental Drug Against Advanced Kidney Cancer
in Straightfromthedoc, on September 28, 2007
...rug axitinib has shown promise against advanced kidney cancer when options are at a dead-end once tumors don't respond to novel therapies.
According to lead investigator Dr Brian I. Rini, ...
Do RFID Chips Cause Cancer?
in The Wireless Weblog, on September 11, 2007
...ies conducted over the past decade or so determined that implanted RFID chips had induced cancerous tumors in mice and rats.
"The transponders were the cause of the tumors," says Keith Joh...
The debate continues: RFID can cause cancer, RFID cannot cause cancer
in The RFID Weblog, on September 11, 2007
...and the embedded chip and even backed their findings by previous studies which stated that cases of tumors were even found in cats and rats which had been chipped. These tumors were witnessed in infla...
Human Source of Stem Cells With Potential To Repair Muscle Damaged by Disease or Injury
in The Biotech Weblog, on September 5, 2007
... in contrast to other stem cell therapies, the myoendothelial cells also showed no tendency to form tumors.
Source: Children's Hospital of Pittsburgh ...
Gene Therapy Clear Amyloid Plaques in Animal Trials
in The Biotech Weblog, on August 31, 2007
...id-busting enzyme known as neprilysin. The skin cells, also known as fibroblasts, "do not form tumors or move from the implantation site," Hemming notes. "They cause no detectable adver...
Polymer Nanoparticle Uptake in an In Vitro 3-D Brain Tumor Co-Culture Model
in The Biotech Weblog, on August 27, 2007
... these techniques the tumor aggregates were found to invade the brain slices in a similar manner to tumors in the body. Having developed the model then the tumor selective uptake of nanoparticles was ...
No Side Effects to Chemo?
in Philoneist, on August 11, 2007
...ausea will be at a minimum. Even better, the nano-tech is being designed to specifically target the tumors, and not all cells in the body as is the case with current chemotherapy.
Even if it's no...
LKB1: New Lung Tumor-Suppressor Gene
in The Biotech Weblog, on August 5, 2007
...rs, do play a role the development of non-small cell lung cancer in mice.
"The LKB1-deficient tumors grew more rapidly and spread more frequently than the others, and comprised all three types o...
MRgFUS of Non-cancerous Uterine Fibroids Provides Long Term Symptom Relief
in Straightfromthedoc, on August 2, 2007
...dy found that the innovative, non-invasive, outpatient treatment for non-cancerous fibroid uterine tumors -called magnetic resonance imaging guided focused ultrasound surgery (MRgFUS) - has been f...
Diagnosing and Treating Cancer Gets Easier Every Day
in Philoneist, on August 1, 2007
American researchers are making waves again with new diagnostic measures for cancer as seen here .
Now they are using a grouping of cancer cell lines from the National Cancer Institute to develop a system that will match tumor profiles to the treatment and lend a better prognosis for th...
Biomedical Engineers Destroy Cancer Cells with Electric Pulses
in The Biotech Weblog, on July 16, 2007
... Rubinsky of the University of California, Berkeley.
According to Dr. Davalos:
"IRE removes tumors by irreversibly opening tumor cells through a series of short intense electric pulses from sm...
Male Hormones Inhibitor May Cure Hard-to-Treat Prostate Cancer
in Straightfromthedoc, on July 9, 2007
...ody - abiraterone - is showing potential in early trials on prostate cancer patients whose tumors continued to grow despite medical or surgical intervention.
As presented last week at the E...
Cancer Cure Moves Forward Right Before Our Eyes
in Philoneist, on June 22, 2007
...
Researchers have come up with something that is going to change the face, literally, of cancer tumors. It is a hologram imaging system that is designed to examine cancer tumor cells while anticanc...
Do wireless technologies cause brain tumors, Cancer and more?
in Tech Without Wires, on June 21, 2007
... Is There Scientific Evidence Linking Cell Phone Use to DNA Damage, Brain Tumors, Alzheimer's Disease, Cancer and More?
You had better check out EMFNEWS.ORG to see from one perspective whether ...
Don't believe everything you read
in Audeamus - How dare we..., on June 16, 2007
...tion on what pesticides are proven to do to humans, including cancer, fertility problems, and brain tumors, plus information on how you can minimize those consequences, go check out the article at Si...
HDAC Inhibitors: Cancer Drug, Can Enhance Long-term Memory
in Straightfromthedoc, on June 7, 2007
...eacetylase (HDAC) inhibitors - cancer drugs currently used in clinical trials to attack cancerous tumors - has been found in mice study by UC Irvine scientists to enhance long-term memory and stre...
Fibroids and Ultrasound
in Well Woman Blog, on June 6, 2007
... According to Adam's Medical Encyclopedia :
Uterine fibroids are non-cancerous tumors that develop within or attach to the wall of the uterus, a female reproductive organ.
Alternatives to Hy...
Flaxseed Reduces Prostate Tumor Growth
in Straightfromthedoc, on June 5, 2007
...tty acids and lignans - flaxseed - has been found effective in stalling the growth of prostate tumors .
According to Wendy Demark-Wahnefried, Ph.D., a researcher in Duke's School of nursin...
Milk for Breast Cancer
in Well Woman Blog, on June 1, 2007
.... The inverse associated in premenopausal women appeared more pronounced for more aggressive breast tumors. ...
Chemicals and Breast Cancer
in Well Woman Blog, on May 22, 2007
... more so when you read the list of potential culprits:
There are 216 chemicals that induced breast tumors in animals. Of these, 97 directly affect humans and include industrial solvents, pesticides, ...
Diabetes Drug Avandia® (rosiglitazone maleate) Boosts Potency of Platinum Chemotherapy
in Daily Diabetic, on May 9, 2007
...Combining a platinum chemotherapy agent and the diabetes drug rosiglitazone halted or shrank mouse tumors as much as three times more effectively than either of the drugs given alone.
Cancers often ...
Nanotechnology and Gene Therapy Against Stage IV Lung Cancer
in The Biotech Weblog, on April 24, 2007
...ody's defense mechanisms. The nanoparticles accumulate mainly in the lungs, particularly in the tumors, where the genes repeatedly express FUS1 tumor-suppressing proteins.
In the study, the media...
Oral Rinse Genetic Test for Head and Neck Cancer
in The Biotech Weblog, on April 23, 2007
... head and neck squamous cell carcinoma (HNSCC). The tes detects CD44, a protein biomarker for HNSCC tumors, and together with the detection of cancer-related altered DNA, could reliably distinguish ca...
Endosulfatase Enzyme Predicts Nasopharyngeal Cancer Survival and Recurrence Rates
in The Biotech Weblog, on April 23, 2007
SULF2 , a recently identified heparin-degrading endosulfatase could be used to predict survival and recurrence rates for nasopharyngeal cancer , according to researchers from the Mayo Clinic Cancer Center.
The researchers examined tumor tissue from 55 patients with squamous cell carcinoma of ...
MRIs for Breast Cancer
in Well Woman Blog, on March 28, 2007
...lling drugs.
Using this novel technique, the researchers predicted with 90 percent accuracy which tumors would respond when treated with ''neoadjuvant'' chemotherapy and which tumors...
TYKERB®: GlaxoSmithKline's Breast Cancer Drug, Approved by the FDA
in The Biotech Weblog, on March 16, 2007
...e following patient population:
patients with advanced or metastatic breast cancer whose tumors overexpress HER2 and who have received prior therapy including an anthracycline, a taxane, an...
USFDA Approved GlaxoSmithKline's Breast Cancer Drug TYKERB®
in Straightfromthedoc, on March 15, 2007
...citabine), for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2 and who have received prior therapy (anthracycline, a taxane, and trastuzumab)...
Peptide Vaccine with Toll-Like Receptor Agonists Against Breast Cancer
in The Biotech Weblog, on February 5, 2007
...ere with a strong killer T cell response.
The vaccine was most effective in preventing spontaneous tumors when it was given once at week eight - along with anti-CD25 antibodies -- when most mice have...
PPAR-gamma Inhibitors: Potential Anti-Cancer Compounds
in The Biotech Weblog, on February 5, 2007
...cer cell growth, reduced the cells' ability to spread through the bloodstream to cause new tumors elsewhere (metastasize) and caused cells to self-destruct, generally within 24 hours. Further expe...
New Tool For Detecting Breast Csncer
in Well Woman Blog, on February 2, 2007
...s those images, searching for abnormalities, including blood vessels that develop to feed cancerous tumors.
"Breast cancer is there for ten years before you have tissue diagnosis," said Int...
Brown Algae Polyphenols May Protect Against Skin Cancer
in The Biotech Weblog, on January 29, 2007
...din E2 cell proliferation levels in the skin," Stoner says, "which corresponds with fewer tumors and small tumors in the treated animals."
In addition, animals fed with BAP had lower i...
