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Stem Cell Therapy Reverse Multipple Sclerosis
in The Biotech Weblog, on January 31, 2009
Photo courtesy of iStockphoto , Image# 6634098 The Telegraph reports of the continuing positive results on the use of stem cells in treating multiple sclerosis in conjunction with a drug called alemtuzumab. The study leader, Dr Richard Burt, described it as a "feasible procedure" tha...
Nanotubes with Stem Cells Accelerate Bone Growth
in The Biotech Weblog, on January 31, 2009
Photo courtesy of iStockphoto , Image# 5176287 Researchers have discovered that using titanium oxide nanotube implants with stem cells can help accelerate bone growth and healing.
During their research, the group of UC San Diego bioengineers and material science experts used a nano-bio techn...
Embryonic-Like Stem Cells From Human Testes?
in Straightfromthedoc, on October 9, 2008
Photo courtesy of iStockphoto , Image# 7406735
Here's one finding that could sidestep the political and ethical obstacles associated with the use of embryonic stem cells : European researchers were able to figure out how to make sperm-producing testicular cells into producing embryon...
Cardiosphere-Derived Stem Cells for Treatment of Heart Disease
in The Biotech Weblog, on September 30, 2008
Photo courtesy of iStockphoto , Aaliya Landholt During the recently held Southern California BioMedical Council (SoCalBio or SCBC) 10th Investor Conference, biotech firm Capricor Inc presented their Cardiosphere-derived Stem Cells or CDC technology , and the multi-billion dollar market potentia...
Banking Your Baby's Umbilical Cord Blood
in Next Nine Months, on September 24, 2008
© Brandt Kurowski During my second pregnancy, I had the chance to chat with other pregnant friends about cord blood banking. Most of us were ambivalent about it, knowing the value of cord blood in providing stem cells that could possibly be used in treating illnesses years down the line...
Poly-D-Lysine Matrix for Growing Animal-Free Stem Cells
in The Biotech Weblog, on August 26, 2008
Scientists have developed an alternative to animal-based materials such as Matrigel-coated plates for culturing the stem cells , which produce cells that are cells unsuitable for medical use. First, they identified a specific signaling pathway, called Rho-Rock, which the hESCs use during colony...
Spinal Cord Stem Cells Identified
in The Biotech Weblog, on July 29, 2008
Stem cells within the spinal cord that could differentiate into more healing cells and fewer scarring cells following an injury, have been identified.
The researchers at MIT and the Karolinska Institute found that neural stem cells in the adult spinal cord are limited to a layer of cube- or co...
Heart Muscle Stem Cells From the Epicardium
in The Biotech Weblog, on June 24, 2008
Credit: Bin Zhou, MD (Children's Hospital Boston) Scientists have identified a new, previously unrecognized group of stem cells that give rise to the different heart muscle cells. These stem cells, the third type of cardiac progenitor identified so far, is located on the surface of the heart ...
Muscle-Derived Stem Cells Used to Sphincter Damage and Restore Continence
in The Biotech Weblog, on May 17, 2008
Scientists from Germany and Austria have successfully used muscle-derived stem cells to repair damage to the urinary sphincter that causes incontinence.
Certain medical procedures, including transurethral resection of the prostate and radical prostatectomy can result in damage to the externa...
Multipotential Stem Cells from Menstrual Blood
in The Biotech Weblog, on April 25, 2008
In the new issue of Cell Transplantation a study demonstrated the potentials of menstrual blood as a source of stromal stem cells with the ability to differentiate into a variety of cell lineages.
Tests showed that MenSCs could differentiate into adipogenic, chondrogenic, osteogenic, ect...
Novocell's Human Stem Cells, Treat Diabetes in Mice
in Daily Diabetic, on April 9, 2008
Based in San Diego, California (USA), Novocell Inc. has found a potential in their human embryonic stem cells for diabetes cure .
As reported by Novocell's team of researchers in the journal Nature Biotechnology:
Human stem cells transformed into nearly normal insulin-producing ...
Hair Follicle Stem Cells Differentiate into Blood Vessels and Smooth Muscle Cells
in The Biotech Weblog, on March 29, 2008
In a paper published in the journal Cardiovascular Research , researchers demonstrate that stem cells isolated from sheep hair follicles contain the smooth muscle cells that could grow into new blood vessels and stem cells from human hair follicles into contractile smooth muscle cells.
...
Human Umbilical Cord Blood Cells Improve Alzheimer's Disease Indices
in The Biotech Weblog, on March 28, 2008
In animal trials, researchers found that umbilical cord blood cell therapy improved the pathology and cognitive decline associated with Alzheimer's disease. According to a report :
Following a series of low-dose infusions of human umbilical cord blood cells into mice with Alzheimer'...
Researchers Identify Cause of Neurofibromatosis Type1
in The Biotech Weblog, on February 18, 2008
Researchers have identified the cells responsible for neurofibromatosis type1 , a genetic disease characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the skin, brain, and other parts of the body.
Researchers have long wondered which of the body'...
Using Dielectrophoresis to Sort Stem Cells
in The Biotech Weblog, on December 20, 2007
Scientists have developed a quicker, easier and more cost-effective method of sorting stem cells using electrodes to identify which cells will turn into specific cell types once they have been transplanted.
The technique used by the scientists, called dielectrophoresis, is based on the premis...
Southern California Stem Cell Scientific Collaboration
in The Biotech Weblog, on November 29, 2007
Six Southern California institutions are collaborating to advance stem cell research by establishing the Southern California Stem Cell Scientific Collaboration (SC3) .
Members of the collaboration include:
University of Southern California
Childrens Hospital Los Angeles
City of Hope
University...
Insulin Resistance: Due to Inflammation, Not Obesity
in Daily Diabetic, on November 10, 2007
...tes.
Find more details from University of California, San Diego .
[Photo Credit: www.bloodlines.stemcells.com ]...
Using Stem Cells to Regenerate Cornea and Treat Genetic Skin Disease
in The Biotech Weblog, on October 25, 2007
During an international meeting of stem cell scientists in Milan, Italian scientists report on the use of stem cells to replace damaged corneal tissues in the eye and to treat Epidermolysis Bullosa, a rare but debilitating genetic disease of the skin characterized by highly fragile and blistering...
GlaxoSmithKline, AstraZeneca and Roche Form Stem Cell Consortium
in The Biotech Weblog, on October 4, 2007
Three of the biggest European pharmaceutical companies - GlaxoSmithKline , AstraZeneca and Roche - have launched the Stem Cells for Safer Medicines , or SC4SM , a collaboration to develop stem cells for safety testing of new drugs through a public-private partnership.
SC4SM is the ...
Human Source of Stem Cells With Potential To Repair Muscle Damaged by Disease or Injury
in The Biotech Weblog, on September 5, 2007
Scientists have isolated stem cells from blood vessels (known as myoendothelial cells) which can be differentiated in the laboratory into muscle, bone and cartilage cells and are thus suitable for use as a potential therapy for muscle injuries and diseases including heart attack and muscle dystro...
Brain Stem Cells and Phenserine May Treat Alzheimer's Disease
in The Biotech Weblog, on August 7, 2007
A team of researchers from the Karolinska Institute in Sweden and the National Institutes of Health discovered that transplanting brain stem cells and treatment with a compound called phenserine may help treat Alzheimer's disease . Previously, it has been shown that brain stem cells transp...
UK National Stem Cell Network
in The Biotech Weblog, on April 19, 2007
Yesterday, the UK National Stem Cell Network (UKNSCN) has been officially launched.
In addition to coordinating the UK's numerous national and regional stem cell research initiatives, the UKNSCN will help to bring together and improve communication between the various sub-disciplines of s...
Early-Stage Sperm Cells from Bone Marrow Stem Cells
in The Biotech Weblog, on April 16, 2007
Scientists have been able to successfully culture early-stage sperm cells from mesenchymal stem cells isolated from the bone Marrow .
For the experiment, Prof Nayernia and his team took bone marrow from male volunteers and isolated the mesenchymal stem cells. These cells have previously ...
Stem Cell Research Enhancement Act of 2007 Passes House
in The Biotech Weblog, on April 14, 2007
Earlier this week, the Stem Cell Research Enhancement Act of 2007 , which would loosen the restrictions on human embryonic stem cell research in the US, passed in the US Senate .
Under the existing policy, federal funds may be used to study only those stem cells taken from embryos des...
Stem Cells May Stop/Reverse Diabetes
in Daily Diabetic, on April 13, 2007
Stem cell therapy tested on type 1 diabetes patients at Northwestern University's Feinberg School of Medicine resulted to foregoing insulin.
This is the first time to demonstrate that Type 1 diabetes can be halted and may be reversed by a stem-cell transplant.
The transplant preserve...
Top Biotech Hubs for 2007
in The Biotech Weblog, on February 26, 2007
Fierce Biotech has released its "Top Five Regions Targeting Biotech Companies" for 2007 .
This is unquestionably a highly subjective list drawn from the headlines that we scour every day for the FierceBiotech newsletter. It takes a significant amount of attention combined with a lo...
Adipose-Derived Stem Cell Therapy for Cardiovascular Disease
in The Biotech Weblog, on February 9, 2007
Cytori Therapeutics , a biotech firm developing stem and regenerative cell therapies for cardiovascular diseases treated their first patient in a hospital in Spain as part of Cytori's randomized clinical trial investigating the safety and feasibility of using adipose-derived stem and regene...
Heart Muscle With Built-In Blood Supply from Embryonic Stem Cells
in The Biotech Weblog, on February 1, 2007
For the first time, a three-dimensional human cardiac tissue complete with blood vessels have been constructed using human embryonic stem cells . This offers potentials for use in studies of cardiac development, function and tissue replacement therapy.
The researchers engineered the heart...
Stem Cells Derived from the Amniotic Fluid
in The Biotech Weblog, on January 8, 2007
Scientists from the Wake Forest University School of Medicine and Harvard Medical School have discovered a new source of stems cells which may be used to create muscle, bone, fat, blood vessel, nerve and liver cells in the laboratory: the amniotic fluid .
Atala and colleagues discovered a smal...
Using Stem Cells to Treat Lower Back Pain Due to Intervertebral Disc Degeneration
in The Biotech Weblog, on December 28, 2006
Most cases of lower back pain are due to intervertebral disc degeneration, wherein the soft tissue separating the vertebrae of the spine become dry and inflexible. Current treatment options only address the symptoms using a combination of pain relievers, physiotherapy or a more invasive pr...
Wisdom Teeth-Derived Stem Cells Regenerate Teeth
in The Biotech Weblog, on December 24, 2006
Using a swine model, dental scientists have been able to regenerate tooth root and supporting periodontal ligaments and restore tooth function using stem cells derived from wisdom teeth.
The technique relies on stem cells harvested from the root apical papilla, which is responsible for the de...
Stem Cells from Adult Hair Follicles as Alternative to Embryonic Stem Cells
in The Biotech Weblog, on December 17, 2006
Scientists have confirmed that adult hair-follicle-derived stem cells (also called epidermal neural CREST stem cells) may be used as an alternative to embryonic stem cells (ESC).
Similar to embryonic stem cells, they have a high degree of plasticity, can be isolated at high levels of pu...
Photoreceptor-Precursor Cell Transplant Can Restore Vision
in The Biotech Weblog, on November 9, 2006
Using mice models, scientists have transplanted photoreceptor-precursor cells directly into the retina of the eyes, thus restoring visual function.
Rather than injecting undifferentiated and uncommitted stem cells into the retina in hopes they would develop into photoreceptors, researchers intr...
2nd Annual Stem Cell Summit
in The Biotech Weblog, on November 8, 2006
What : 2nd Annual Stem Cell Summit
When : Feb. 12-13, 2007
Where : Wyndham San Diego at Emerald Plaza
This two-day conference is expected to bring together more than 35 companies as well as Physicians and investors who will speak and present on the latest developments in embryonic an...
Fat-Derived Stem Cells May be Used for Breast Reconstruction in Breast Cancer Patients
in The Biotech Weblog, on October 29, 2006
University of Pittsburgh researchers are exploring the potential of using fat-derived stem cells to regenerate new breast tissue. If successful, this approach may represent a better option to recostructive surgery among breast cancer patients.
Dr. Rubin and his colleagues are focusing their effo...
Stem Cells Treat Macular Degeneration in Rats
in The Biotech Weblog, on September 23, 2006
Advance Cell Technology , the biotech firm who has recently announced having successfully generated embryonic stem cell lines without destroying the embryos , now says it has used human embryonic stem cells to treat eye disorders in rats .
"We have developed a technology that we hope can...
Human Embryonic Stem Cell Lines Derived Without Destroying Embryos
in The Biotech Weblog, on August 24, 2006
Scientists have developed a technique that allows stem cell lines to be produced from cells extracted from early (8-10 cell) stage embryos. The new method, described in a paper published in this weeek's Nature , generates embryonic stem cell lines without interfering with the embryo's ...
Singapore Biotech Firm Produces Clinical-Grade Stem Cells For Human Use
in The Biotech Weblog, on July 29, 2006
Singapore biotech company , ES Cell International Pte Limited (ESI) , has produced four new clinically-compliant human embryonic stem cell (hESC), with another four lines in the pipeline. Previously existing embryonic lines have been in contact with mouse cells, and are therefore unsuit...
Multipotent Adult Stem Cells from Human Hair Follicles
in The Biotech Weblog, on July 13, 2006
Scientists have identified a potential new source of multipotent adult stem cells: hair follicles .
The mutipotent stem cells grow as masses the investigators call hair spheres . After growing the "raw" cells from the hair spheres in different types of growth factors, the investigat...
Nature Special Issue: 25 years of Embryonic Stem Cells
in The Biotech Weblog, on June 28, 2006
Marking the 25th anniversary of two papers reporting the first isolation of mouse ES cells, which led to the development of the first knockout mice and heralded a revolution in developmental biology and genetics, Nature is releasing a Special Stem Cells Issue . The special issue is featur...
Bone Marrow Stem Cells May Repair Retinal Damage
in The Biotech Weblog, on June 12, 2006
It is widely believed among scientists that like brain cells, the retinal pigment epithelium (RPE) , a cell layer that plays a vital role in eyesight is a nonrenewable resource. In diseases of the retina, including age-related macular degeneration , it is thought that the damage cannot be reve...
Use of Liquid Crystals In Controlling Differentiation of Stem Cells
in The Biotech Weblog, on March 10, 2006
Liquid crystals are not just used to display information on cell phones, monitors and other electronic equipment alone, but also to report the differentiation of embryonic stem cells in real time.
Differentiation is the process by which embryonic stem cells gradually turn into function ...
France Adjusts Stem Cell Regulations
in The Biotech Weblog, on February 24, 2006
Human cloning is banned in France. Bioethics laws established in August, 2004 authorized human embryonic stem cell research, but using stem cell lines imported from abroad.
However, the Agence de Biomédecine announced recently that new conditions are set, at least for the next fiv...
Administration of Stem Cells In Acute Myocardial Infarction Therapy
in The Biotech Weblog, on January 16, 2006
Myocardial infarction , more commonly known as heart attack, is a heart ailment that results when an area of heart muscle is damaged because of an inadequate supply of oxygen to that area. It is estimated that in US alone, approximately 1 million patients visit the hospital each year with a...
Hedgehog Proteins Potential Target for Obesity and Osteoporosis Therapy
in The Biotech Weblog, on January 12, 2006
Proteins that belong to the hedgehog signaling pathway (named for SEGA's video game character Sonic the Hedgehog because of the appearance of mutant phenotype which causes a Drosophila embryo to be covered with pointy denticles, resembling a hedgehog) have been previously shown ...
Hwang's human Stem Cells Were All Fakes
in The Biotech Weblog, on January 11, 2006
I've resisted posting about Korean stem-cell and cloning expert, Woo Suk Hwang, in this weblog, amidst the controversy that erupted towards the end of 2005. Until now, the extent of the supposed faking of results, has not been clear.
Today, the results of the investigatory committee...
Using Stem Cells To Treat Brain Injury in Children on Clinical Trials
in The Biotech Weblog, on December 23, 2005
Using stem cells derived from their bone marrow , children suffering from traumatic brain injury will be treated in a first clinical trial of its kind. The clinical trial is FDA-approved and builds on previous results on in vitro and animal testing showing that bone-marrow derived ste...
Fruitfly Gut Stem Cells Similar to Human's
in The Biotech Weblog, on December 13, 2005
In an article published online last week in Nature (abstract only, full-text available upon subscription), scientists from the Carnegie Institution 's Department of Embryology have found that not only do adult fruitflies have stem cells lining their gut like humans do, but that
...
StemCells, Inc. Receives Manufacturing License for Cell Processing Facility in California
in The Biotech Weblog, on August 31, 2005
...
StemCells, Inc. today announced that it has received a manufacturing license for its cell processing facility from the State of California Department of Health Services, Food and Drug branch...
1-800-Stem-Cells.com : Stem Cells and Cord Blood Banking
in The Biotech Weblog, on August 29, 2005
...e latest on stem-cell technology and treatments, as well as cord-blood banking, it's at www.1800stemcells.com. No dashes. Otherwise, you end up with GoDaddy.
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