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Forscher konnten erstmals die Ausbreitung von HI-Viren stoppen
in Daily Innovation, on August 11, 2008
...kheiten erprobt. Die Forscher stellen ihre Arbeit im Fachmagazin "Cell" vor.
Mit RNAi lassen sich Gene schnell und zielsicher abschalten - eben auch solche welche für Entstehung von Krankh...
14-3-3zeta, Potential Lung Cancer Gene Target
in The Biotech Weblog, on December 27, 2007
... Researchers have identified a gene target called 14-3-3zeta for selective anti-cancer drugs. Using RNAi techniques, they discovered that when 14-3-3zeta is turned off, lung cancer cells become less a...
Molecular Biology of the Gene, 6th Edition
in The Biotech Weblog, on December 20, 2007
...regulatory RNAs (Chapter 18) and genomics and systems biology (Chapter 20). These chapters focus on RNAi and microRNAs, the opportunities offered by the new generation of genome technologies, and the ...
First Antisense Drug for Chemotherapy-Responsive Chronic Lymphocytic Leukemia
in The Biotech Weblog, on February 19, 2007
...
A phase III clinical trial for oblimersen (trade name: Genasense ), the first "antisense" drug to be tested in chronic lymphocytic leukemia (CLL), shows promise as an adjunct therap...
Using RNAi To Engineer More Nutritious Wheat Varieties
in The Biotech Weblog, on January 10, 2007
Using RNA interference technology, scientists have identified a gene in wheat called Gpc-B1 that regulates its nutritional content.
Collaborators working under the direction of wheat breeder and professor Jorge Dubcovsky of the University of California-Davis found that kernels harvested from t...
Using RNAi Technology Against BSE and CJD
in The Biotech Weblog, on December 10, 2006
...ephalopathy (BSE, also known as "mad cow disease") and Creutzfeldt-Jakob Disease.
Using RNAi technology, they have been able to demonstrate in vitro that the genes coding for PrPsc, an abn...
RNAi Technology Yields Edible Cottonseed
in The Biotech Weblog, on November 21, 2006
...
Using RNAi technology , agricultural researchers have been able to suppress the expression of gossypol , a toxic protein , in cottonseed to a level considered to be safe for consumption, t...
幽默的科学同样也是科学
in Wangtam, on October 16, 2006
...时的口香糖，太阳穴就开始抽筋，然而啄木鸟每天用脑袋敲击木头 1.2 万次，却从来不会头痛，这是为什么？加州大学的研究者 Ivan R.Schwab 凭借这一课题获得了今年的"谐趣诺贝尔"鸟类学奖 ---- 他通过深入的研究发现，啄木鸟头骨和脑部的构造、脑部组织附近的肌肉一起构成了一个完美的减震器 ---- 如果我们也有这样一个脑壳，那医院就再也没有脑震荡患者了。
是的，我们需...
3rd Annual RNAi Europe Conference and Exhibition
in The Biotech Weblog, on September 21, 2006
... What : 3rd Annual RNAi Europe Conference and Exhibition
When : 28-29 September 2006
Where : Prague, Czech Republic
Twenty speakers, over 25 exhibitors and more than 40 poster presentat...
More than 400 Biotechnology Drugs and Vaccines Under Trials
in The Biotech Weblog, on August 16, 2006
...s targeting asthma, lupus and various types of cancer
vaccines designed against AIDS and cancer
antisense products as potential treatments for cancer and heart disease
gene therapy testing in ca...
Sirna Therapeutics Licenses microRNA Technology From UMMS
in The Biotech Weblog, on May 15, 2006
... anti-RISC oligonucleotides. These patents describe methods that can be used not only for advancing RNAi basic research, but also for developing miRNA-based therapeutics.
This will definitely strengt...
ISIS 301012 Shows Favorable Phase 2 Clinical Trial Results Against Atherosclerosis
in The Biotech Weblog, on May 2, 2006
...es triglycerides , an additional risk factor for coronary artery disease."
ISIS 301012 is an antisense drug that inhibits the expression of a protein called apoB-100 , which has been shown to...
Gene Therapy and RNAi To Treat Sickle Cell Disease
in The Biotech Weblog, on January 3, 2006
Scientists from the Memorial Sloan-Kettering Cancer Center used a combination of stem cell-based gene therapy and RNA interface technology to genetically reverse sickle cell disease (SCD) in human cells.
Sickle cell disease is a hereditary blood disorder characterized by sickle-shaped ...
RNA Antagonist SPC2996 Receives FDA Approval For Phase I/II Trials
in The Biotech Weblog, on November 8, 2005
Santaris Pharma , a Danish biopharmaceutical company developing anti-caner drugs using RNA-interference technology, received US FDA approval for its international Phase I/II study of SPC2996 , an Investigational New Drug (IND) against Chronic Lymphocytic Leukaemia (CLL).
CLL is a type of...
Sirna Therapeutics Patents Vector Expressed siRNA Against Huntington's Disease
in The Biotech Weblog, on October 5, 2005
...oped by Targeted Genetics.
Sirna Therapeutics is a clinical-stage biotechnology company developing RNAi-based therapies for serious diseases and conditions, including age-related macular degenerati...
RNA Nanoparticles Against Cancer
in The Biotech Weblog, on September 15, 2005
...no Letters and Human Gene Therapy , scientists from Purdue University combined nanotechnology and RNAi to propose a treatment against cancer cells. Thy used three RNA strands, one of which is a smal...
Aging Genes Identified
in The Biotech Weblog, on July 28, 2005
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...in worms, at least. Using RNAi screening, researchers have identified 23 new longevity genes by screening the genome of Caenorhabditis elegans , a favorite model animal of geneticists. Among...
Symposium: Regulatory RNA in Biology and Human Health
in The Biotech Weblog, on August 28, 2007
...group of researchers working in RNA interference, X-chromosome inactivation and naturally occurring antisense transcripts will look at our current understanding of the mechanisms of action and biogene...
Second Annual Meeting of the Oligonucleotide Therapeutics Society
in The Biotech Weblog, on June 27, 2006
... discovery, preclinical and clinical research for oligonucleotide-based therapeutics such as RNAi, Aptamers, Antisense, and immunostimulatory compounds such as CpG.
Special sessions will be de... ...linical and clinical research for oligonucleotide-based therapeutics such as RNAi, Aptamers, Antisense, and immunostimulatory compounds such as CpG.
Special sessions will be devoted to:
Oli...
RNAi and Antisense RNA Therapy from the Tangled Bank
in The Biotech Weblog, on June 19, 2006
...this blog, and both can be found at Fight Aging :
RNA Interference as the New Gene Therapy
Antisense RNA Therapies
Both articles provide a short introduction into this novel technology i...