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20 Cholesterol Regulating Genes Identified
in The Biotech Weblog, on July 8, 2009
© micahb37 Using RNA interference technology, researchers from the European Molecular Biology Laboratory have identified 20 genes involved in cholesterol metabolism , potentially leading to new treatments for heart disease and other cholesterol-related diseases.
Of the 20 genes the scientists...
How biotech companies can reduce supply chain risk?
in Supplychainer, on June 25, 2009
... I don't think I have written any post on biotech supply chain management in this blog (at least I don't remember any), but seeing this nice piece in ICIS website became a motivation to w...
Fiber for Nerve Repair Derived from Chitosan and Polyester
in The Biotech Weblog, on June 19, 2009
Researchers have developed a promising new material that can be used to repair severed nerves by combining chitosan , a compound found in the shells of crabs and shrimp, and polycaprolactone , a strong, flexible, biodegradable polyester commonly used in sutures. The hybrid fiber combines the b...
Azotobacter vinelandii Genome Sequence
in The Biotech Weblog, on June 18, 2009
© MASH DnArt Researchers have successfully sequence the genome of Azotobacter vinelandii , a nitrogen fixing bacterium found in soil. The data gathered will help advance research on nitrogen fixation and other biochemical processes, using A. vinelandii as model organism.
A. vinelandii has o...
Blood Test for Aging Protein p16p16INK4a
in The Biotech Weblog, on June 17, 2009
© Divine in the Daily Previously, researchers haveidentified a key protein, called p16INK4a, that increase in mammalian organs as as cells and tissues age. Recently, they have found out that the protein is also present in human blood and is strongly correlated both with chronological age and wi...
Jasmonic Acid Treatment Cuts Down Pesticide Use
in The Biotech Weblog, on June 9, 2009
© jilly40uk US agricultural company Becker Underwood, in collaboration with Plant Bioscience Limited, now holds worldwide exclusive licence on the use of jasmonic acid as a natural seed treatment to help cut down on pesticide use on some commercially-important agricultural crops.
Researchers a...
OTC Prostate Cancer Test Kit in the Making
in The Biotech Weblog, on June 5, 2009
Researchers are developing a diagnostic test for prostate cancer wherein gold nanoparticles screen for the same cancer-related protein marker that is screened for by the FDA-approved Prostate-Specific Antigen (PSA) test.
Huo and her team at the UCF lab developed the new technique involving go...
Global Rejection of Genetically Engineered Wheat
in The Biotech Weblog, on June 3, 2009
Farmers, consumers and civil society organizations in Australia, Canada and the U.S. released a joint statement confirming their collective commitment to stop commercialization of genetically engineered (GE) wheat .
Here's the summary statement:
In light of our existing experience with ge...
Eight Genes That Help Predict Patients Response to Melanoma Treatment
in The Biotech Weblog, on May 31, 2009
A group of researchers have identified eight genes that help predict a melanoma patient's response to treatment .
Dr. Tawbi and his colleagues examined the tumor tissues of 21 patients with metastatic melanoma, some of whom responded to chemotherapy and some who did not. Once the cases wer...
Adult Bone Marrow Stem Cells Can Repair Heart Tissue
in The Biotech Weblog, on May 29, 2009
© denn Using an animal model, researchers have shown that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue and thus reverse damages due to heart failure by doubling myocytes, or heart cells, and reducing cardiac tissue injury by 60 percent.
"Injecting ...
New HIV Microbicide Can Be Produced in Transgenic Plants
in The Biotech Weblog, on May 29, 2009
© Sully Pixel Scientists have developed a new anti-HIV drug as well as a possible means of producing the drug in large quantities using transgenic plants.
In the research paper, Ma and colleagues describe how they combined two protein microbicides (b12 monoclonal antibody and cyanovirin-N) in...
P[acman]-Generated Gene Libraries for Drosophila melanogaster
in The Biotech Weblog, on May 25, 2009
Using a tool called P[acman] , group of researchers has established a library of clones covering most of the genome of Drosophila melanogaster (fruit fly), an organism widely used in genetics research.
P[acman]- developed by Dr. Koen Venken (http://flypush.imgen.bcm.tmc.edu/lab/koenv/index...
Redder Antioxidant-Richer Lettuce Using LEDs
in The Biotech Weblog, on May 21, 2009
© Leeks 'N' Bounds A team of plant physiologists has developed a method of producing redder- and thus healthier, anti-oxidant-richer - lettuce using ultraviolet light-emitting diodes (LEDs) .
To create red leaf lettuce plants enriched with these compounds, Britz purchased low-power LE...
Anti-Inflammatory Constituents of Ginseng Identified
in The Biotech Weblog, on May 16, 2009
© centralasian Scientists have identified immunologically active components in ginseng, an herb used in traditional Chinese and other Asian medicine.
Allan Lau led a team of researchers from the University of Hong Kong who identified seven ginseng constituents, ginsenosides , which showed imm...
Golden Rice is an Effective Source of Vitamin A
in The Biotech Weblog, on May 15, 2009
Golden Rice is a genetically modified plant developed to contain more beta-carotene in the grains, seen as a viable method of alleviating vitamin-A deficiency particularly in developing countries. In its current form, Golden Rice contains 35 micrograms of beta-carotene per gram. But how much o...
Bioscience Education in America: A State by State Analysis
in The Biotech Weblog, on May 12, 2009
...repared and supported by Battelle. BIO commissioned the report and had the input and support of the Biotechnology Institute.
WHEN: Monday, May 18, 2009, 2 p.m. EDT
WHERE: BIO 2009 International Co...
Bacteria with Multiple Antibiotic Resistance in Waste Treatment Plants
in The Biotech Weblog, on May 10, 2009
© DefMo Researchers have discovered increasing populations of bacteria with multiple resistance to antibiotics in waste water treatment plants. They found the so-called superbugs-bacteria resistant to multiple antibiotics-up to 100 yards downstream from the discharge point into the Huron River....
Lung Cancer Susceptibility Gene Identified
in The Biotech Weblog, on May 2, 2009
Researchers have identified a gene linked to increased lung cancer susceptibility and development . This gene, called RGS17, could result in a genetic predisposition to develop lung cancer particularly in those with a strong family history of the disease.
Using a genetically altered mouse mod...
Walnuts May Help Fight Breast Cancer
in The Biotech Weblog, on April 27, 2009
© tvol In an animal study, consumption of walnuts has been demonstrated to help ward off breast cancer in mice .
Researchers led by Elaine Hardman, a cell biologist at Marshall University School of Medicine in Huntington, West Virginia, compared breast cancer incidence in mice eating a di...
Urine Metabolite Identifies Smokers with Higher Lung Cancer Risk
in The Biotech Weblog, on April 27, 2009
© Saudi... Researchers have identified a metabolite in urine called NNAL that might predict risk of Lung cancer among smokers.
To evaluate the impact of NNAL, researchers identified 246 current smokers who later developed lung cancer and 245 smokers who did not develop lung cancer during...
New Agricultural Biotechnology Blog
in The Biotech Weblog, on April 20, 2009
... The Council for Biotechnology Information has launched a blog dedicated to agricultural biotechnology news and information for the 2009 BIO International Convention in Atlanta, Georgia, May ...
Full-sized House using GluBam Technology
in The Biotech Weblog, on April 15, 2009
In Changsha, Hunan Province, China now stands a full-sized California-style home made of bamboo, using the GluBam® technology, tagged by Popular Science in 'Best of What's New in 2008'.
Xiao's GluBam® technology utilizes the modern processing procedures to integrate the round, ...
Varnish Alternative Derived from Glycerin
in The Biotech Weblog, on April 9, 2009
© Elsie esq. German researchers have developed a varnish alternative in which the majority of petrochemical components have been substituted by vegetable oils and sugars. It has identical properties to the conventional varnishes used today and is hard-wearing, scratch-proof and resistant to c...
Banana Briquettes
in The Biotech Weblog, on April 8, 2009
© choyaw99 Researchers have developed a method of converting banana crop waste into briquettes as a source of fuel.
First, the banana skins and leaves are mashed to a pulp in a hand-operated domestic meat mincer. This pulp is mixed with sawdust to create a mouldable material - in Rwanda it wo...
Google to Invest in Biotechnology
in The Biotech Weblog, on April 2, 2009
...velop, to comanage Google Ventures. The other managing partner, Bill Maris, who has a background in biotechnology and healthcare, will be based at Google's corporate headquarters in Mountain View,...
A Web 2.0 Obituary?
in TJ's Weblog, on April 2, 2009
...nown already:
- cloud computing (although recently over hyped, it's long term very viable)
- biotech has yet to show a broad range of success stories
- mobile will remain tricky as long as ther...
Microbes Convert Carbon Dioxide and Electricity to Methane
in The Biotech Weblog, on March 31, 2009
Researchers have developed microbial electrolysis cells using Archaea species that could use the current to convert carbon dioxide and water to methane without any organic material, bacteria or hydrogen usually found in microbial electrolysis cells.
The researchers created a two-chambered cel...
Marker that Predicts Breast Cancer Metastasis
in The Biotech Weblog, on March 28, 2009
Researchers have identified a new marker for breast cancer metastasis called TMEM , for Tumor Microenvironment of Metastasis. These findings could lead to the first test to predict the likelihood of breast cancer metastasis via the bloodstream.
The Weill Cornell investigators set out to build o...
Licorice Compound May Prevetn Colon Cancer
in The Biotech Weblog, on March 24, 2009
A compound found in licorice has been demonstrated to help prevent colon cancer in mice trials. The compound works by inhibiting the enzyme 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2), which is highly expressed in the colon.
The researchers examined expression of 11βHSD2 in human colo...
Pharma CI Conference & Exhibition 2009
in The Biotech Weblog, on March 18, 2009
... Pharma CI Conference & Exhibition is THE INDUSTRY'S GOLD STANDARD for senior level pharma, biotech, and device professionals seeking the latest news and the rare chance to network with all th...
Bioremediation of Chromium-Contaminated Waste with Acetic Acid
in The Biotech Weblog, on March 13, 2009
Photo courtesy of iStockphoto , Image# 3765679 Scientists have discovered that the addition of dilute acetic acid or vinegar can help jumpstart bioremediation of chromium-contaminated industrial wastewater .
"Our treatment method reconverts the oxidised chromate to a non-soluble state, w...
How Cranberry Prevents Urinary Tract Infections
in The Biotech Weblog, on March 12, 2009
Photo courtesy of iStockphoto , Image# 5466776 Cranberries and cranberry juice have been documented to help fight urinary tract infections. An earlier study revealed that tannins found in cranberries prevent bacteria from adhering to the lining of the urinary tract .
In a laboratory set up, th...
Prognostic Test for Frontotemporal Dementia
in The Biotech Weblog, on March 10, 2009
Photo courtesy of iStockphoto , Image# 6952418 A blood test has been developed to predict the risks of frontal lobe dementia (Frontotemporal Dementia, FTD), a form of dementia that occurs most frequently in patients younger than 65. The test is based on previous findings showing that a genetic d...
Gene Therapy for Obesity
in The Biotech Weblog, on March 10, 2009
Photo courtesy of iStockphoto , Image# 7126655 Scientists may have found a promising new treatment for obesity using gene therapy . They have discovered that a particular gene called BDNF , can result in improved insulin sensitivity , reduced fat mass and weight loss when active in the hypo...
200,000 Rice Mutants Available for Study
in The Biotech Weblog, on March 6, 2009
Photo courtesy of iStockphoto , Image# 4796039 Scientists are organizing a repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the rice genome. Two hundred thousand rice mutants are now available and have been ...
Biomarkers for Severity of Chikungunya Fever Identified
in The Biotech Weblog, on March 5, 2009
Photo courtesy of iStockphoto , Image# 7107223 Researchers have identified three specific biomarkers which can provide an accurate indication of the severity of Chikungunya fever (CHIKF), a viral illness that, like dengue fever, is transmitted by mosquitoes.
Based on blood samples obtained ...
Caffeine Offers Skin Cancer Protection
in The Biotech Weblog, on February 27, 2009
Photo courtesy of iStockphoto , Image# 6660710 In a study published this week in the Journal of Investigative Dermatology , researchers investigated the mechanism by which caffeine may confer protection against skin cancer .
For the study, Nghiem's team looked at caffeine's effect on ...
How Capsaicin Interacts with Pain Receptors
in The Biotech Weblog, on February 27, 2009
Photo courtesy of iStockphoto , Image# 7560169 New research published in PLoS Biology further expounds on capsaicin's role in chronic pain relief . According to a related report :
"The receptor acts like a gate to the neurons. When stimulated it opens, letting outside calcium enter...
New Raspberry Variety: Moutere Red Raspberry
in The Biotech Weblog, on February 26, 2009
Photo courtesy of iStockphoto , Image# 5788741 A team of plant breeders from Canada and New Zealand has developed a new variety of red raspberries dubbed 'Moutere' Red Raspberry .
The new variety boasts of high yields of large, uniform size, bright red berries, suitable for consumption...
Lactic Acid Bacteria as Vehicle for Anthrax Vaccine
in The Biotech Weblog, on February 24, 2009
Photo courtesy of iStockphoto , Image# 407156 Researchers have discovered that lactic acid bacteria, commonly found in dairy products, can also be used as a vehicle for an oral vaccine against anthrax , and possibly other types of viruses and pathogens. According to the researchers, "the a...
Genetic Sequencing of Cold Virus
in The Biotech Weblog, on February 19, 2009
Photo courtesy of iStockphoto , Image# 195814 Scientists have successfully mapped the genome of all known human rhinoviruses , which causes the common cold which in turn is responsible for about half of all asthma cases and is a factor in other upper and lower respiratory tract illnesses such a...
RHAMM Protein Removes Wrinkles
in The Biotech Weblog, on February 13, 2009
Scientists have discovered that a protein which plays a role in cancers and tissue repair may also hold potential in removing skin wrinkles. The protein, called RHAMM, for Receptor for Hyaluronan Mediated Motility, may one day replace Botox treatment, which carry such unpleasant side-effects as ...
Using Biotechnology in Cultural Heritage Conservation
in The Biotech Weblog, on February 10, 2009
...itage Conservation Forum held this week in Caracas, Venezuela, curators will be collaborating with biotech scientists to find ways to restore and prevent the decay of art and cultural artefacts using...
Isolongifolenone: A Natural Repellent of Ticks and Mosquitoes
in The Biotech Weblog, on February 9, 2009
Photo courtesy of iStockphoto , Image# 5006157 Researchers have identified a powerful insect repellent derived from a natural compound found in the Tauroniro tree ( Humiria balsamifera ) of South America. The compound, isolongifolenone , has been shown to deter biting of mosquitoes and to repe...
FDA Approxes ATryn, First Drug from a Genetically Engineered Animal
in The Biotech Weblog, on February 7, 2009
The Food and Drug Authority has approved ATryn , the first ever transgenically produced therapeutic protein and the first recombinant antithrombin approved in the U.S.
ATryn is indicated for the treatment of patients with hereditary antithrombin deficiency, undergoing high-risk surgical or c...
Biomaterials Asia 2009
in The Biotech Weblog, on February 1, 2009
What: Biomaterials Asia 2009
When: 5-8 April 2009
Where: Regal Airport Hotel, Hong Kong
This event, with keynote speakers drawn from the world's best scientists, will provide an unparalleled opportunity for researchers, technologists and clinicians in the fields of bioengineering, m...
Stem Cell Therapy Reverse Multipple Sclerosis
in The Biotech Weblog, on January 31, 2009
Photo courtesy of iStockphoto , Image# 6634098 The Telegraph reports of the continuing positive results on the use of stem cells in treating multiple sclerosis in conjunction with a drug called alemtuzumab. The study leader, Dr Richard Burt, described it as a "feasible procedure" tha...
Nanotubes with Stem Cells Accelerate Bone Growth
in The Biotech Weblog, on January 31, 2009
Photo courtesy of iStockphoto , Image# 5176287 Researchers have discovered that using titanium oxide nanotube implants with stem cells can help accelerate bone growth and healing.
During their research, the group of UC San Diego bioengineers and material science experts used a nano-bio techno...
Nanosensor for Skin Based Glucose Monitoring
in The Biotech Weblog, on January 30, 2009
Researchers from Draper Laboratories have developed an injectable nanosensor that can be injected into the skin to monitor an individual's blood-sugar level.
The material consists of 120-nanometer polymer beads coated with a biocompatible material. Within each bead is a fluorescent dye...
First Clinical Trial Using Stem Cell Therapy for Spinal Cord Injuries
in The Biotech Weblog, on January 28, 2009
Photo courtesy of iStockphoto , Image# 2845362 The FDA has approved the world's first clinical trial on the use of stem cell therapy for patients with acute spinal cord injury. Geron Corporation will conduct a Phase I multi-center trial designed to establish the safety of GRNOPC1 in ...
Gene Therapy for Rheumatoid Arthritis
in The Biotech Weblog, on January 27, 2009
Photo courtesy of iStockphoto , Image# 852788 A study published in the journal Human Gene Therapy reports of the first clinical evidence that gene therapy reduces symptoms in patients with rheumatoid arthritis , based on data from two patients. The experiment build on a previous study publish...
Three Genes Linked to Obesity Identified
in The Biotech Weblog, on January 23, 2009
Photo courtesy of iStockphoto , Image# 3457127 Based on a genetic study of 1,380 Europeans, reseachers have identified 3 genes that increase risk of early-onset obesity in children, and morbid obesity in adults .
"The idea was not just to look at run-of-the-mill obesity, but look for gene...
Ben Gurion University and Primafuel Collaborate to Produce Fuel from Microalgae
in The Biotech Weblog, on January 22, 2009
Photo courtesy of iStockphoto , Image# 450318 Ben-Gurion University of the Negev (BGU) and Primafuel, Inc. , a California-based company that develops renewable fuels, have entered a multi-year, multi-million dollar technology-licensing and development agreement .
The collaboration is focuse...
Hydramycin: New Antibiotic Compound from Hydra
in The Biotech Weblog, on January 20, 2009
A new antimicrobial compound has been isolated from the freshwater animal Hydra . The compound, called hydramacin-1, shares virtually no similarity with any other known antibacterial proteins except for two other antimicrobials found in leech, and has been shown in laboratory studies to be hi...
FDA Approves Savella for treatment of Fibromyalgia
in The Biotech Weblog, on January 16, 2009
Photo courtesy of iStockphoto , Image# 2902632 The FDA has approved a new drug for the management of fibromyalgia. Savella™ (milnacipran HCl), developed by FOREST LABORATORIES , Inc. and Cypress Bioscience, Inc. , is a selective serotonin and norepinephrine dual reuptake inhibitor.
Two US...
MicroBiome Analysis Center to Link Chronic Diseases to Microbiomes
in The Biotech Weblog, on January 14, 2009
Photo courtesy of iStockphoto , Image# 6906975 A new molecular ecology facility at Mason called the MicroBiome Analysis Center (MBAC) aims to catalog the human microbiome - the population of microorganisms living within the human body- and try to correlate it with chronic diseases such as obes...
Nominations Open for the Biotech Humanitarian Award
in The Biotech Weblog, on January 13, 2009
... BIO is inviting nominations to the Biotech Humanitarian Award . The award aims to recognize a biotech professional- a scientist, researcher, academic, entrepreneur, financier, philanthropist or...
Black Raspberry Extract May Help Prevent Esophageal Cancer
in The Biotech Weblog, on January 8, 2009
Photo courtesy of iStockphoto , Image# 7776625 In an animal study, researchers attribute the chemo-preventive properties of black raspberries to anthocyanins, a class of flavonoids found in the fruit. This is one of the first experiments demonstrating the correlation between anthocyanins and can...
Business of Biotech Conference At Moffitt Cancer Center
in The Biotech Weblog, on January 5, 2009
... Photo courtesy of iStockphoto , Image# 234885
What: 3rd Annual Business of Biotech Conference
When: 7:30 a.m. to 12:30 p.m. January 29, 2009
Where: Vincent A. Stabile Research Building at Moffi...
Artificial Bone Marrow in a Test Tube
in The Biotech Weblog, on December 24, 2008
Researchers have developed an artificial bone marrow that could continuously produce red and white blood cells in vitro .
The substance grows on a 3-D scaffold that mimics the tissues supporting bone marrow in the body, said Nicholas Kotov, a professor in the U-M departments of Chemical...
Liquid Wood Suitable for Toy Manufacture
in The Biotech Weblog, on December 21, 2008
Credit: TECNARO GmbH Researchers at the Fraunhofer Institute for Chemical Technology ICT in Pfinztal and the Fraunhofer spin-off TECNARO GmbH have developed a material called ARBOFORM®, a type of " liquid wood " or bio-plastic that can safely be used in the manufacture of toys. It is ma...
Industrial Production of Succinic Acid Genetically Modified Bacteria
in The Biotech Weblog, on December 21, 2008
...The technology produces industrial quantities of succinic acid using the principles of "white biotechnology" i.e., production without the use of petroleum.
"In this process, we're...
11 New Cardiovascular Risk Gene Variants Identified
in The Biotech Weblog, on December 19, 2008
Photo courtesy of iStockphoto , Image# 6148437 In addition to 19 other variants previously reported, 11 new gene variants have been identified that are associated with three blood lipids measured to determine cardiovascular disease risk (low-density lipoprotein (LDL) cholesterol, high-density li...
Hydrocyanine Fluorescent Dyes to Detect Reactive Oxygen Species
in The Biotech Weblog, on December 16, 2008
Researchers have developed new fluorescent probes called hydrocyanines that can be used to detect and measure the presence of reactive oxygen species - molecules implicated in a variety of inflammatory diseases, including cancer and atherosclerosis- in living cells, tissue samples and in vivo.
...
Brain Enzyme Regulates Appetite and Weight Gain
in The Biotech Weblog, on December 14, 2008
Scientists have determined that an enzyme in the brain called p70 S6 Kinase 1 or S6K may play a role in preventing weight gain and obesity. The researchers injected rats with special viruses that selectively raise or lower S6K activity and found that an increased S6K activity led to reductio...
New Bacterial Species in Raw Milk
in The Biotech Weblog, on December 11, 2008
Photo courtesy of iStockphoto , Image# 5514120 Microbiologists have identified new species of bacteria in raw milk . One of these bacteria, Chryseobacterium oranimense , can grow at cold temperatures and secretes enzymes that may spoil milk. Furthermore, since raw milk is refrigerated after co...
UK Validation Study Initiated on Pathwork Tissue of Origin Test
in The Biotech Weblog, on December 10, 2008
Photo courtesy of iStockphoto , Dr. Heinz Linke
Pathwork Diagnostics announced a collaboration with Guy's and St Thomas' NHS Foundation Trust in London to conduct the first research study on the Pathwork Tissue of Origin Test in the UK.
The proof-of-concept study with the test, wh...
Hops Extract Lupulone as Antibiotic in Poultry
in The Biotech Weblog, on December 8, 2008
Photo courtesy of iStockphoto , Image# 4090990 Researchers have found that hops extracts have antimicrobial compounds such as lupulone that may be used to to control levels of the pathogenic bacteria Clostridium perfringens in the gut of chickens.
[The researchers]delivered different concen...
How Broccoli Compound Fights Cancer
in The Biotech Weblog, on December 6, 2008
Photo courtesy of iStockphoto , Image# 3214889 UC Berkley scientists have identified a compound found in broccoli which may be responsible for its anti-cancer properties. The compound, indole-3-carbinol (I3C), is already undergoing clinical trials in humans based on results from animal trial...
Genetic Blood Test Provide More Accurate Evaluation For Cystic Fibrosis Patients
in The Biotech Weblog, on December 3, 2008
Photo courtesy of iStockphoto , Image# 2049412 A preliminary "proof-of-principle" trial demonstrated the feasibility of a genetic blood test to demonstrate cystic fibrosis patients' response to therapy.
Using microarray gene analysis of the blood samples, the researchers identifie...
