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FDA Approved New Kidney Cancer Drug: Torisel™ (temsirolimus) by Wyeth
in Straightfromthedoc, on June 1, 2007
...e only marketed cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase [a key protein in cells that regulates cell proliferation, cell growth and cell survival] ... ... and much needed option for treatment."
The said Phase II clinical trial, where Torisel™ have demonstrated prolonged survival in renal cell carcinoma patients - as recently r eported at the New...
In Utero Chemical Genetics to Prevent Birth Defects
in The Biotech Weblog, on February 16, 2007
...ated in mice that it may be possible to correct birth defects such as a cleft palate by injecting rapamycin into the mother to restore the functions of a protein called GSK-3 beta, which play a ro... ... In a study published in the Feb. 11 advance online edition of Nature , scientists have demonstrated in mice that it may be possible to correct birth defects such as a cleft palate by injecting...
Immunosuppressant Rapamycin Have Anti-Angiogenic Properties, Potential Anti-Cancer Therapy
in The Biotech Weblog, on August 15, 2006
... Scientists from the Beth Israel Deaconess Medical Center (BIDMC) have demonstrated in mice that rapamycin (sirolimus, sold as Rapamune by Wyeth ), an immunosuppresor used in organ trans... ... Scientists from the Beth Israel Deaconess Medical Center (BIDMC) have demonstrated in mice that rapamycin (sirolimus, sold as Rapamune by Wyeth ), an immunosuppresor used in organ tra...
Rapamycin May Protect Heart Against Tissue Damage
in The Biotech Weblog, on July 7, 2006
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Rapamycin (also called sirolimus , marketed as Rapamune® by Wyeth) is a peptide produced by Streptomyces hygroscopicus , originally developed as an antibiotic, but is more commonly used as a...