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Results for interleukin receptor. Search took 0.51 seconds.
Biomarkers for Severity of Chikungunya Fever Identified
in The Biotech Weblog, on March 5, 2009
...in January 2008, the scientists found that the levels of three specific biological factors, namely interleukin-1 beta, (IL-1β) , interleukin-6 (IL-6) and RANTES , distinguished patients with the s...
How Capsaicin Interacts with Pain Receptors
in The Biotech Weblog, on February 27, 2009
...ounds on capsaicin's role in chronic pain relief . According to a related report :
"The receptor acts like a gate to the neurons. When stimulated it opens, letting outside calcium enter th...
RHAMM Protein Removes Wrinkles
in The Biotech Weblog, on February 13, 2009
...and tissue repair may also hold potential in removing skin wrinkles. The protein, called RHAMM, for Receptor for Hyaluronan Mediated Motility, may one day replace Botox treatment, which carry such unp...
Lack of Sleep Is Genetically Linked To Type 2 Diabetes
in Daily Diabetic, on December 8, 2008
...e molecular details of how sleep can change blood sugar levels. The key, it appears, is a melatonin receptor, a protein on the outside of cells that senses melatonin in the blood and triggers sleep- o...
Gpr41 Receptor Molecule in Intestines, Target for Anti-Obesity Drugs?
in The Biotech Weblog, on October 20, 2008
... Photo courtesy of iStockphoto , Sebastian Kaulitzki Scientists have identified a receptor molecule present in the intestinal wall called Gpr4 , that, when activated by wastes of gut bacteria,...
Pentazocine May Protect Against Diabetes-Related Retinal Damage
in Daily Diabetic, on September 25, 2008
...entazocine to one that wasn't. Even to the untrained eye, the differences are dramatic.
Sigma receptors are ubiquitous in the body, but their role and what naturally activates them are unknowns. ...
Chronische Darmentzuendungen: Ursachen besser verstanden
in Das Gesundheits-Weblog, on August 29, 2008
... grp-78 festgestellt. Gleichzeitig fehlt der entzündungshemmende Immunbotenstoff Interleukin-10. Die gestörte Interaktion dieser beiden Akteure scheint mit Schuld an chronischer Darmentzündung zu sein...
Researchers Identify Key Allergy Gene
in Allergies, on August 29, 2008
...ic diseases .
The newly discovered FCER1A Gene encodes the alpha chain of high affinity IgE receptor , which plays a major role in controlling allergic responses. The team of scientists led by...
Protein Transporter for Lutein and Zeaxanthin, Identified
in The Biotech Weblog, on July 25, 2008
...s carrots, papaya, squash and peaches.
According to the study, the protein SR-B1 , or scavenger receptor class B, type 1 , plays a central role in transporting these nutrients from the bloodstream ...
Entereg® (Alvimopan): FDA-Approved for Post-Surgery Bowel Function
in Straightfromthedoc, on May 23, 2008
...urgery .
Entereg® (Alvimopan) is a first-in-class small molecule, peripherally-acting mu opioid receptor (PAM-OR) antagonist designed to block the adverse side effects of opioid analgesics on the GI...
Plant Flavonoid Luteolin Reduce Inflammatory Response in the Brain
in The Biotech Weblog, on May 21, 2008
...g showed that luteolin was shutting down production of a key cytokine in the inflammatory pathway, interleukin-6 (IL-6). The effects of luteolin exposure were dramatic, resulting in as much as a 90 pe...
Using Skin Flaps to Deliver Anti-Cancer Drugs
in The Biotech Weblog, on May 15, 2008
...w us to reprogram skin flaps, using gene therapy, to provide a blueprint for anti-tumor agents like Interleukin-12 to be produced in the tumor to kill cancer, while avoiding adverse side effects,"...
An Aspirin A DAy: Keeps Breast Cancer Away?
in Straightfromthedoc, on May 1, 2008
... © +lyn
Daily intake of aspirin may lower women's risk of developing estrogen receptor-positive (ER+) breast cancers only and not in other types.
Around 75% of breast cancers are estrogen r...
New Molecule May Lead to Anti-Heart Attack Drug
in Straightfromthedoc, on April 21, 2008
... suggests that it is possible to dissolve the clots by a way of a clot-busting pill that attacks a receptor on the blood cells' surface.
When such kind of a pill happen, high risk patients can ta...
Gene Therapy May Treat Cocaine Addiction
in The Biotech Weblog, on April 17, 2008
...sing gene therapy, researchers have demonstrated in rats that increasing the levels of dopamine D2 receptors in the brain can reduce use of cocaine by 75 percent .
"By increasing dopamine D2 r...
Oncology Diagnostics By AviaraDx
in The Biotech Weblog, on April 14, 2008
... launched for the classification of metastatic cancer and identification of patients with estrogen receptor positive (ER+) breast cancer who are at high risk of recurrence and also those unlikely to r...
Caffeine Against Multiple Sclerosis?
in The Biotech Weblog, on April 10, 2008
...he animal model for the human disease Multiple Sclerosis (MS).
Caffeine is a well-known adenosine receptor blocker, and the researchers believe results show the importance of this molecule in permitt...
FDA Investigates Link Between Use of Singulair and Behavioral Changes Including Suicidal Tendencies
in Allergies, on March 28, 2008
...thinking and behavior) and suicide. Singulair is a once-a-day medicine classified as as leukotriene receptor antagonists used to treat asthma and symptoms of allergic rhinitis.
Over the past year, th...
Two Protein Receptors Control Stomach Relaxation Identified
in The Biotech Weblog, on March 5, 2008
... Scientists have identified 2 protein receptors in a guinea pig - P2Y1 and P2Y11 - that relax the gut and thus allow it to accommodate a bigger meal. these receptors are also present in humans and m...
Arcalyst: New Orphan Drug FDA-Approved for Treatment of Rare Inflammatory Syndromes
in Straightfromthedoc, on February 28, 2008
...re condition known as Cryopyrin-Associated Periodic Syndrome or CAPS .
Arcalyst ( rilonacept, an Interleukin-1 blocker ) is now approved for the long term treatment of two Cryopyrin-Associated Peri...
Gene Plays a Role in Hair Loss Identified
in The Biotech Weblog, on February 27, 2008
... and identified homozygous truncating mutations in P2RY5, which encodes an orphan G protein-coupled receptor. Furthermore, we identified oleoyl-L-alpha-lysophosphatidic acid (LPA), a bioactive lipid, ...
(Pro3)GIP Injections May reverse Obesity and Diabetes
in The Biotech Weblog, on January 6, 2008
... Scientists have identified a gastric inhibitory polypeptide (GIP) receptor antagonist called (Pro3)GIP , which has been demonstrated in an animal model to be capable of promoting weight loss, imp...
Hormone Blocker Found May Prevent Obesity and Diabetes
in Daily Diabetic, on January 4, 2008
...The hormone called gastric inhibitory polypeptide (GIP) receptor blockade has been found capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model.
...
Lack of a Gene Triggers Overeating and Obesity
in Straightfromthedoc, on January 2, 2008
...According to Dr. Rios:
"Prior to this study, we knew that the global lack of BDNF and/or its receptor during development leads to overeating and obesity in young mice. However, it remained uncl...
Peptide Drug Aimed at Two Bioterror Agents
in The Biotech Weblog, on December 21, 2007
...ing human cells, and thus preventing an outbreak.
... Drs. Porotto and Moscona knew that when the receptor-binding molecule on the virus-simply called "G"-binds to the surface of the cell,...
mGluR5 Mutation Reverses Fragile X Syndrome
in The Biotech Weblog, on December 20, 2007
...brake" would allow another protein that stimulates this process, called metabotropic glutamate receptor 5 (mGluR5), to function unchecked.
Their tests on the double mutant mice revealed that the...
Enhanced HIV Vaccine, Helped Monkeys Kick AIDS-like Symptoms
in Straightfromthedoc, on November 28, 2007
...sylvania School of Medicine .
This multi-year study found that the addition of a molecule called Interleukin-15 effectively boosts the effects of a vaccine derived from the DNA of simian HIV. The ...
Serotonin Receptors, Potential Target for Diabetes and Obesity Drugs?
in The Biotech Weblog, on November 8, 2007
...In animal trials, a compound called m-chlorophenylpiperazine (mCPP) which triggers serotonin receptors in the brain has been found to improve glucose tolerance and lower insulin levels in obese and di...
Capsaicin Drug Candidate Under Trials for Post-Operative Pain
in The Biotech Weblog, on October 31, 2007
...iate post-operative pain .
Nerve cells that sense a type of long-term throbbing pain bear a receptor, or gate, called TRPV1. Capsaicin binds to that receptor and opens it to enter only those p...
Exposure to Sunlight May Reduce Risk for Breast Cancer
in Well Woman Blog, on October 30, 2007
...risk of advanced breast cancer in light-skinned women, the results show. Mutations of the vitamin D receptor gene did not affect the association.
However, this association was not seen in women with ...
New Male Contraceptives Under Development
in The Biotech Weblog, on September 29, 2007
... fertility. However, it doesn't guarantee successful pregnancy after long-term use.
vitamin A receptor blocker, developed by Columbia University researchers. A drug that had been abandoned by a ...
Genetic Basis of Susceptibility to Acute Urinary Track Infections
in The Biotech Weblog, on September 18, 2007
...asis for susceptibility to acute pyelonephritis, a severe form of urinary track infection. The IL-8 receptor, CXCR1 , has been identified as a candidate gene in previous animal trials. In human studi...
Why Some Diabetes Drugs Increase Risk of Heart Failure
in Daily Diabetic, on September 17, 2007
...Diabetes drugs that are agonists of the peroxisome proliferator activated receptor (PPAR) gamma such as pioglitazone and rosiglitazone are associated with increased risk of heart failure.
...
The Gut has Glucose Receptors Too
in Daily Diabetic, on September 4, 2007
...Our tongue has a taste receptor. The taste receptor T1R3 and the taste G protein gustducin are critical to sweet taste in the tongue.
What is interesting are the new findings by researchers in th...
Cannabis May Treat Skin Allergies
in Allergies, on August 16, 2007
...at may contribute to the increased [cutaneous (skin) contact hypersensitivity (CHS)] in cannabinoid-receptor deficient mice, the researchers performed a series of experiments which showed that mouse s...
Inflammatory Cytokines: Markers that May Predict Type 2 Diabetes in Still-healthy People
in Daily Diabetic, on August 16, 2007
...ll predict diabetes in still-healthy individuals:
tumor necrosis factor-alpha (TNF-á)
interleukin-6 (IL-6)
high-sensitivity C-reactive protein (hs-CRP)
Each one of these cytokines (...
Histamine2 Receptor Antagonists (H2A): Linked to Cognitive Impairment
in Straightfromthedoc, on August 6, 2007
... Histamine2 receptor antagonists (H2A) are one class of drugs that blocks stomach acid.
H2As, including including ranitidine and famotidine , are among the most popular medications pres...
Aliskiren-Valsartan Combo, Better at Lowering Blood Pressure
in Straightfromthedoc, on July 25, 2007
... the combination of aliskiren and valsartan, and combinations of aliskiren with other angiotensin receptor blockers, on possible benefits beyond treating hypertension.
...and warned:
"...
BLOODchip®: DNA Biochip That Ensures Safety in Blood Transfusions
in The Biotech Weblog, on July 11, 2007
...liminates the risk of adverse reactions due to incompatibility in blood groups between donor and receptor in blood transfusions.
With the aim of guaranteeing safety during blood transfusions,...
Fibrinogen: Blood-Clotting Protein, Inhibits Spinal Cord Regeneration
in The Biotech Weblog, on July 10, 2007
...f injury -- begins the process of inhibiting axonal growth by binding to the beta 3 integrin receptor. This binding, in turn, induces the activation of another receptor on the neuronal cells, c...
Human and Animal SARS Viruses-Blocking Antibodies, Identified in Humans
in The Biotech Weblog, on July 8, 2007
...human antibodies that bind to a region on the SARS virus' spike glycoprotein that is called the receptor binding domain (RBD):
S230.15 - was found in the blood of a patient who had been infect...
Interleukin-12 (IL-12): The Answer to Food Allergies?
in Allergies, on July 6, 2007
...itute of Food Research in Norwich led by Dr. Claudio Nicoletti have identified a vital molecule - Interleukin-12 (IL-12) - that can be a potential target for food allergy Therapy .
According...
Retinaldehyde: Vitamin A Derivative, May Protect Against Diabetes
in Daily Diabetic, on June 17, 2007
...etes.
Exactly how retinaldehyde works is not clear, but it seems to be related to PPARs, retinoid receptors, and general metabolism. The researchers found that Raldh-negative animals have higher met...
Fish Oil for Colitis
in Well Woman Blog, on June 12, 2007
...reased levels of omega-6 oils, in turn, leads to increased levels of the pro-inflammatory cytokines interleukin-1 and leukotriene LTB-4. High levels of these cytokines are seen in arthritis, Crohn'...
New Genetic Risk Factor for Coeliac Disease Identified
in The Biotech Weblog, on June 11, 2007
...ons.
What they found is that healthy individuals more often have a protective DNA sequence in the interleukin-2 and interleukin-21 gene region than individuals with coeliac disease . Interleukin-2 a...
Gene Therapy for Treating Neuropathic Pain
in The Biotech Weblog, on June 4, 2007
...ly engineered herpes simplex virus (HSV) to deliver the gene for part of the human glycine receptor (GlyR) , a receptor found primarily on the surface of nerve cells in the spinal cord and th...
Sodium Iron EDTA: Better than Electrolytic Iron in Boosting Iron Levels
in Straightfromthedoc, on May 29, 2007
...with it - haemoglobin and plasma ferritin concentrations, and amounts of plasma soluble transferrin receptor. Low-dose NaFeEDTA also improved these iron status indicators but to a lesser extent. Elect...
Engineered Protein Against Staphylococcus aureus Toxin
in The Biotech Weblog, on May 23, 2007
...toxin in considered as a potential bioterrorism agent.
"Our approach was to take these receptors that bind to the toxins and to try to make them higher affinity and therefore act as effec...
Plant Chemical Harmine, Fights Diabetes without Side Effects
in Daily Diabetic, on May 11, 2007
...by activating a central promoter of fat tissue production called peroxisome proliferator-activated receptor ã (PPARã) . This process allows storage of lipids that would otherwise deposit on other tis...
Merck Licenses Coley Pharma's VaxImmune for $4 Million
in The Biotech Weblog, on April 13, 2007
...on, and milestone fess of up to $33 million plus royalties.
VaxImmune is a proprietary Toll-like receptor 9 (TLR9) agonist designed to induce both an enhanced antigen-specific antibody response an...
Thema Uebergewicht: Bauchfett foerdert Entzuendung
in Das Gesundheits-Weblog, on March 16, 2007
...mmelt und der Leber zuführt. Dieses Blut wies 50 Prozent höhere Spiegel des Botenstoffs Interleukin-6 auf als Blut aus einer Armarterie, berichten die Forscher im Fachblatt "Diabetes".
Je h...
RAMP1: The Protein that Promotes Migraine
in Straightfromthedoc, on March 12, 2007
...n called RAMP1.
Too much of this protein seem to "turn up the volume" of a nerve cell receptor's response to a neuropeptide - called CGRP (calcitonin gene-related peptide) - that can...
Genetically Engineered Lactococcus may Induce Food Tolerance
in Allergies, on March 5, 2007
...te that the oral administration of Lactococcus lactis , which were bioengineered to secrete murine interleukin-10 (IL-10), could inhibit and/or stop sensitisation and subsequently, food allergies. Th...
Bioengineered Non-Pathogenic Gut Bacteria May Regulate Food Tolerance
in Straightfromthedoc, on March 5, 2007
...actococcus lactis (a non-pathogenic gut bacteria), when bioengineered to produce anti-inflammatory interleukin-10 (IL-10) can be a potential regulator for food tolerance , thereby significantly...
Darmentzündung, Darmkrebs: neues Heilverfahren durch Hemmung eines Botenstoffs?
in Das Gesundheits-Weblog, on February 7, 2007
...inzelheit nach, um aufs Ganze schließen zu können. Untersucht wurde der Botenstoff Interleukin-8 (IL-6), ein Zytokin (Signalstoff, der in den Zellen Bewegungsvorgänge bewirkt), er spielt offenbar (man...
Peptide Vaccine with Toll-Like Receptor Agonists Against Breast Cancer
in The Biotech Weblog, on February 5, 2007
...emonstrated the efficacy of a peptide vaccine against breast cancer. The vaccine includes toll-like receptor agonists as well as antibodies to blunt other aspects of the immune system that might inter...
PPAR-gamma Inhibitors: Potential Anti-Cancer Compounds
in The Biotech Weblog, on February 5, 2007
... Scientists have identified a group of compounds called peroxisome proliferator-activated receptor-gamma (PPARγ) inhibitors which may help treat colorectal cancer, and potentially cancers of the e...
Zinc May Not Help Diabetes Symptoms After All
in Daily Diabetic, on January 26, 2007
... zinc levels in diabetic patients are reduced.4,5,6,7 Zinc is involved in the regulation of insulin receptor-initiated signal transduction mechanisms3 and insulin receptor synthesis.
And against:
...
Inhaled Steroids Preferred Initial Treatment for Children's Asthma
in Allergies, on January 26, 2007
...nist (100 mcg fluticasone each morning plus 50mcg salmeterol twice daily), and a leukotriene receptor antagonist (montelukast).
The results support the current asthma clinical guidelines, whic...
MediciNova Initiates Phase II Trial on Insomnia Pill
in The Biotech Weblog, on January 25, 2007
...eatment of insomnia.
MN-305 is a potent and highly-selective full agonist at the serotonin 5-HT1A receptor under development both for the treatment of insomnia as well as for anxiety disorders such...
In Silico Screening of Chinese Herbs Using Random Forest
in The Biotech Weblog, on January 25, 2007
...e to be performed to confirm their findings.
More focused studies, using techniques such as ligand-receptor docking, are also required, as are theoretical approaches to questions such as the possible...
Blood Pressure Drugs May Worsen Diabetes
in Daily Diabetic, on January 19, 2007
...already at risk for the condition, U.S. researchers report.
According to the report, angiotensin- receptor blockers (ARBs) and angiotensin-converting-enzyme (ACE) inhibitors are the blood press...
Antibody Used To Prevent Type 1 Diabetes
in Daily Diabetic, on January 16, 2007
...recognizes and helps fight infections and other foreign substances in the body - directed against a receptor known as CD137 on the surface of a type of immune cell called T-cells. Treating NOD mice wi...
Estrogen and the Hormone Leptin Has Same Appetite-Curbing Mechanism of Action
in Straightfromthedoc, on January 9, 2007
...at of leptin, estrogen's effect on feeding and obesity is independent from leptin or the leptin receptor.
Impaired estrogen signaling in the brain may be the cause of metabolic changes during men...
Liver X Receptor: A Dual Role Glucose Sensor
in Straightfromthedoc, on December 30, 2006
... be just the kind of device that diabetics are dreaming of?
That kind of sensor - called Liver X Receptor - have been first described by scientists at the Scripps Research Institute which could ...
How Black Cohosh Reduce Hot Flashes
in The Biotech Weblog, on December 23, 2006
...lying this effect, and found that elements of the herb could bind to the human 'mu' opiate receptor ", which affects neurotransmitters important for temperature regulation.
Although the...
Orthopäden: Berufsbild im Wandel - bei Arthrose auch Eigenbluttherapie
in Das Gesundheits-Weblog, on November 11, 2006
...tionsphase (Ruhezeit) anfangen, körpereigene entzündungshemmende Zytokine, vor allem Interleukin 1, zu produzieren. Den so veränderten Serumcocktail zentrifugiert man dann (gibt ihn in eine Zentrifug...
Trout - Catch Them Before They Catch You
in The Outdoor Weblog, on October 30, 2006
......
...Trout have an acute sense of hearing that is well worth understanding. Trout have two sound receptors. The first one runs along the length of the fish's body. This receptor picks up freque...
Why Eating Feels So Good: The Neurobiological Explanation
in Straightfromthedoc, on October 24, 2006
...as the ventral tegmental area (VTA).
Tamas Horvath and colleagues showed that ghrelin bound its receptor on neurons of the VTA and triggered their production of dopamine.
Importantly, infusion o...
NIH Scientists Identified a Human Protein that Helps the Spread of Chickenpox And Shingles Virus
in Straightfromthedoc, on October 22, 2006
...cella-zoster virus called insulin-degrading enzyme , attaches to a cellular protein, using it as a receptor to enter and infect cells.
NIAID virologist Jeffrey I. Cohen, M.D., and NIAID research fel...
