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Personal Genomics & Privacy Survey
in The Biotech Weblog, on September 30, 2009
...has created a new online, interactive survey regarding values & attitudes related to Personal Genomics , and are inviting you to participate.
In this survey, you will be asked questions about is...
Tablet-Based Treatment for Diabetes
in The Biotech Weblog, on September 1, 2009
© Sarah G... Scientists have developed what could be the first tablet-based treatment for children and adults with Type 1 diabetes . Early animal trials indicate that the anti-Ras FTS compound is effective in restoring insulin production in animal models ― which could spell an end to the d...
Bone-setting Glue Derived from Cloned Sandcastle Worm Genes
in The Biotech Weblog, on August 20, 2009
Credit: Fred Hayes Scientists have developed a synthetic version of an adhesive formed by a marine worm, Phragmatopoma californica . This worm secrets a glue to build a tubelike shell out of bits of sand, broken shells and other mineral debris. By cloning the gene for the proteins making up ...
Exxon: The Genetics of Algae
in IfEnergy, on July 30, 2009
...cided to sink $600 million into algae as a source of biofuel and it is partnering with Synthetic Genomics on the issue, acording to Matter Network. The oil company's initial investment (that can...
IVF Success Lies in the Genes
in Next Nine Months, on July 26, 2009
© Neeta Lind Before you spend money, time and emotions, you naturally would want to know: what are the chances that IVF will work for you? Scientists say that the answer may be found in your blood .
"We found that the gene expression profiles in blood of patients at the time of pituitary...
Genetically Modified Salt-Tolerant Cereal Crops
in The Biotech Weblog, on July 10, 2009
...iving in the same conditions.
Credit: Image courtesy of the Australian Centre for Plant Functional Genomics (ACPFG)/University of Adelaide
...
20 Cholesterol Regulating Genes Identified
in The Biotech Weblog, on July 8, 2009
© micahb37 Using RNA interference technology, researchers from the European Molecular Biology Laboratory have identified 20 genes involved in cholesterol metabolism , potentially leading to new treatments for heart disease and other cholesterol-related diseases.
Of the 20 genes the scientists...
Genome-Wide Karyomapping for Detecting Cystic Fibrosis in Embryos
in The Biotech Weblog, on June 30, 2009
© drsuparna In the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam, scientists report of an embryo test that can screen for cystic fibrosis as well as aneuploidy. According to the researchers, genome-wide karyomapping simultaneously detects inherita...
Azotobacter vinelandii Genome Sequence
in The Biotech Weblog, on June 18, 2009
© MASH DnArt Researchers have successfully sequence the genome of Azotobacter vinelandii , a nitrogen fixing bacterium found in soil. The data gathered will help advance research on nitrogen fixation and other biochemical processes, using A. vinelandii as model organism.
A. vinelandii has o...
Eight Genes That Help Predict Patients Response to Melanoma Treatment
in The Biotech Weblog, on May 31, 2009
A group of researchers have identified eight genes that help predict a melanoma patient's response to treatment .
Dr. Tawbi and his colleagues examined the tumor tissues of 21 patients with metastatic melanoma, some of whom responded to chemotherapy and some who did not. Once the cases wer...
P[acman]-Generated Gene Libraries for Drosophila melanogaster
in The Biotech Weblog, on May 25, 2009
Using a tool called P[acman] , group of researchers has established a library of clones covering most of the genome of Drosophila melanogaster (fruit fly), an organism widely used in genetics research.
P[acman]- developed by Dr. Koen Venken (http://flypush.imgen.bcm.tmc.edu/lab/koenv/index...
Lung Cancer Susceptibility Gene Identified
in The Biotech Weblog, on May 2, 2009
Researchers have identified a gene linked to increased lung cancer susceptibility and development . This gene, called RGS17, could result in a genetic predisposition to develop Lung cancer particularly in those with a strong family history of the disease.
Using a genetically altered mouse...
Google to Invest in Biotechnology
in The Biotech Weblog, on April 3, 2009
...d range of fields, from search and advertising to mobile computing to medical records and personal genomics . Its target is to invest $100 million in the coming year, with the boston area being o...
Prognostic Test for Frontotemporal Dementia
in The Biotech Weblog, on March 10, 2009
Photo courtesy of iStockphoto , Image# 6952418 A blood test has been developed to predict the risks of frontal lobe dementia (Frontotemporal Dementia, FTD), a form of dementia that occurs most frequently in patients younger than 65. The test is based on previous findings showing that a genetic d...
200,000 Rice Mutants Available for Study
in The Biotech Weblog, on March 6, 2009
Photo courtesy of iStockphoto , Image# 4796039 Scientists are organizing a repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the rice genome. Two hundred thousand rice mutants are now available and have been ...
Genetic Sequencing of Cold Virus
in The Biotech Weblog, on February 19, 2009
Photo courtesy of iStockphoto , Image# 195814 Scientists have successfully mapped the genome of all known human rhinoviruses , which causes the common cold which in turn is responsible for about half of all asthma cases and is a factor in other upper and lower respiratory tract illnesses such a...
Three Genes Linked to Obesity Identified
in The Biotech Weblog, on January 24, 2009
Photo courtesy of iStockphoto , Image# 3457127 Based on a genetic study of 1,380 Europeans, reseachers have identified 3 genes that increase risk of early-onset obesity in children, and morbid obesity in adults .
"The idea was not just to look at run-of-the-mill obesity, but look for gene...
11 New Cardiovascular Risk Gene Variants Identified
in The Biotech Weblog, on December 19, 2008
Photo courtesy of iStockphoto , Image# 6148437 In addition to 19 other variants previously reported, 11 new gene variants have been identified that are associated with three blood lipids measured to determine cardiovascular disease risk (low-density lipoprotein (LDL) cholesterol, high-density li...
Genetic Blood Test Provide More Accurate Evaluation For Cystic Fibrosis Patients
in The Biotech Weblog, on December 3, 2008
Photo courtesy of iStockphoto , Image# 2049412 A preliminary "proof-of-principle" trial demonstrated the feasibility of a genetic blood test to demonstrate cystic fibrosis patients' response to therapy.
Using microarray gene analysis of the blood samples, the researchers identifie...
LMID1 Gene Protects Against Lung Cancer
in The Biotech Weblog, on December 3, 2008
Photo courtesy of iStockphoto , Image# 703709 University of Nottingham researchers have identified a gene that may help protect against lung cancer . By comparing lung cancer tissues from patients with the disease and comparing it to healthy lung tissues, they found that the LIMD1 gene was mi...
deCODE BreastCancer Genetic Diagnostic Test Launched
in The Biotech Weblog, on October 13, 2008
Photo courtesy of iStockphoto , Dawn Poland deCoODE Genetics launched deCODE BreastCancer™ , a new non-invasive tool for assessing risk of the common forms of breast cancer.
The deCODE BreastCancer™ test measures seven widely replicated single-letter variations (SNPs) in the human genom...
Non-Invasive Blood Test for Fetal Genetic Anomalies
in The Biotech Weblog, on October 12, 2008
Photo courtesy of iStockphoto , Sylvia Cook Researchers have developed a new prenatal blood test that accurately detected Down syndrome and two other serious chromosomal defects in a small study of 18 pregnant women. The test scan fetal DNA present in the mother's blood to detect chromosom...
Biomarkers for Oral Cancer in Saliva
in The Biotech Weblog, on September 30, 2008
...t; Hu said. "We have demonstrated a new approach for cancer biomarker discovery using saliva proteomics ."
Researchers are currently working on a device to detect these biomarkers, a po...
GIF1 Gene: Key To High-Yield Rice
in The Biotech Weblog, on September 29, 2008
A gene in rice that controls the size and weight of rice grains has been identified, and may thus be useful for breeding high-yield rice.
"The GIF1 gene is responsible for controlling the activity of the enzyme invertase, which is located in the cell wall and converts sucrose to subs...
Protein Biomarkers in Urine for Bovine Spongiform Encephalopathy (BSE)
in The Biotech Weblog, on September 11, 2008
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Photo courtesy of iStockphoto, Rob Broek Researchers have identified proteins in urine samples which may be used as an indicator of the presence and progress of Bovine Spongiform Encephalopathy (BSE) disease in cattle.
The scientists analysed the proteins in urine samples taken from ...
Researchers Identify Key Allergy Gene
in Allergies, on August 29, 2008
Photo courtesy of iStockphoto, Image# 6591906
German researchers report having identified a major gene for allergic diseases .
The newly discovered FCER1A Gene encodes the alpha chain of high affinity IgE receptor , which plays a major role in controlling allergic responses. The team ...
FRO7 Gene Vital to Photosynthesis and Iron Metabolism in Plants
in The Biotech Weblog, on August 27, 2008
Photo courtesy of iStockphoto, Andrejs Zemdega Researchers have shown that a gene called FRO7 is vital for efficient photosynthesis and for iron metabolism , processes necessary for producing a healthy plant and a nutritious food source.
In this study, Guerinot and her colleagues provide mole...
Netzwerke der Zellen: Toponomik, neues Forschungsgebiet
in Das Gesundheits-Weblog, on 19.08.08
Da will ich doch gleich noch etwas Neues bieten. ein ganz neues Forschungsgebiet, und das ist nun wirklich Grundlagenforschung im engeren Sinne: oder haben Sie schon etwas von Toponomik gehört? Bisher steht es noch nicht einmal in wikipedia (vielleicht sollte ich einen Eintrag schreiben?* was für m...
Kiwi Fruit's Expressed Sequence Tags Published
in The Biotech Weblog, on August 4, 2008
... are likely to have the type of fruit we want."
The genetic data have been published in BMC Genomics .
Source ...
Genetic Sequencing Companies Join 1000 Genomes Project
in The Biotech Weblog, on June 11, 2008
Photo courtesy of iStockphoto, Image# 3676922
Three DNA sequencing companies have joined an international research consortium called 1000 Genomes , aimed at creating a new map of the human genome that will provide a view of biomedically relevant DNA variations at a resolution unmatch...
Genetic Tests to Detect and Predict Recurrence Likelihood of Lung Cancer
in The Biotech Weblog, on May 25, 2008
Two research studies presented during the recently held American Thoracic Society's 2008 International Conference in Toronto point to diagnostic tests for lung cancer: a blood test for accurately detecting lung cancer in its early stages, and a genetic test to predict the likelihood that c...
Use of Genomics to Control Dandruff
in The Biotech Weblog, on May 23, 2008
... The article Dandruff Genomics in a recent issue of The Scientist featured Procter & Gamble scientist Thomas Dawson and the role of genomics in the development of anti- Dandruff shamp...
Gene for Kidney Failure Identified
in The Biotech Weblog, on April 30, 2008
Scientists have identified a gene known as Jund , which controls the activity of a group of cells thought to be responsible for potentially severe inflammation of the kidney. This discovery could offer a route for tackling the auto-immune destruction of kidney tissue which can occur in lupus ...
RCSB Protein Data Bank Archives 50,000th Molecule Structure
in The Biotech Weblog, on April 10, 2008
The backbone structure of the infectious epsilon15 virus (PDB ID 3c5b, in photo) is the most recent addition to the Protein Data Bank (PDB) based at Rutgers, The State University of New Jersey, making it the 50,000th molecule structure released into the only worldwide repository for the three-...
Flour Beetle Genome Sequence
in The Biotech Weblog, on March 30, 2008
An international team of researchers has sequenced the genome from the red flour beetle Tribolium castaneum , making it the first beetle and the first insect pest , whose genome has been sequenced.
A large international research consortium consisting of 64 research groups from 14 coun...
Salivary Proteomics as a Diagnostic Tool
in The Biotech Weblog, on March 26, 2008
...ing the "complete" salivary proteome , a set of proteins in human ductal saliva.
Saliva proteomics and diagnostics is part of a nationwide effort to create the first map of every human pro...
Two Protein Receptors Control Stomach Relaxation Identified
in The Biotech Weblog, on March 5, 2008
Scientists have identified 2 protein receptors in a guinea pig - P2Y1 and P2Y11 - that relax the gut and thus allow it to accommodate a bigger meal. these receptors are also present in humans and may serve as targets for developing drugs to aid in weight management and preventing obesity.
Dr Br...
Gene Plays a Role in Hair Loss Identified
in The Biotech Weblog, on February 27, 2008
Researchers have identified a gene responsible for a rare hereditary form of hair loss known as hypotrichosis simplex . From the abstract of the paper published in Nature :
Hypotrichosis simplex is a group of nonsyndromic human alopecias. We mapped an autosomal recessive form of this ...
DNA Test for Assessing Prostate Cancer Risks Possible
in The Biotech Weblog, on January 25, 2008
A new genetic test for the early detection or prostate cancer may soon be developed. Until now, a patient's risks of having prostate cancer is based on PSA tests which has a relatively low sensitivity.
Now, however, a research group at Karolinska Institutet and their American colleagues ha...
Preliminary Soybean Genome Released
in The Biotech Weblog, on January 22, 2008
The U.S. Department of Energy Joint Genome Institute (DOE JGI) has released a preliminary assembly and annotation of the soybean genome to the greater scientific community to enable bioenergy research.
The current assembly (representing 7.23x coverage), gene, set, and browser are collec...
Novel Genetic Variants Linked to Heart Disease
in The Biotech Weblog, on January 14, 2008
An international collaboration of scientists have discovered more than 25 genetic variants in 18 genes linked to cholesterol and lipid levels . Such findings may help in estimating an individual's genetic risk of heart disease, as well as lead to a better understanding of cholesterol metabol...
Osteocrin Protein Controls Bone Growth
in The Biotech Weblog, on December 23, 2007
Researchers have discovered protein that controls bone growth, and thus may be used as the basis for finding treatment for people with bone diseases affecting skeletal growth.
Osteocrin is a small protein produced by the body's bone-forming cells, or osteoblasts. In this study, mice...
The Human Microbiome Project
in The Biotech Weblog, on December 22, 2007
The National Institutes of Health (NIH) today announced the official launch of the Human Microbiome Project , the collective genomes of all microorganisms present in or on the human body.
Part of the NIH's Roadmap for Medical Research, the Human Microbiome Project will award a total of $1...
Molecular Biology of the Gene, 6th Edition
in The Biotech Weblog, on December 21, 2007
...molecular biology have been included. Two all-new chapters discuss regulatory RNAs (Chapter 18) and genomics and systems biology (Chapter 20). These chapters focus on RNAi and microRNAs, the opportuni...
Genetic Map for Aging in Mice
in The Biotech Weblog, on November 30, 2007
Using gene arrays, researchers have identified genes whose activity changes with age in 16 different mouse tissues. The study, published in PLoS Genetics , uses a newly available database called AGEMAP to document the process of aging in mice at the molecular level.
As an organism ...
In Utero Arsenic Exposure Leads to Increased Cancer Risk
in Next Nine Months, on November 24, 2007
A recent study published in PLoS Genetics this week indicates that women who whose water supplies were contaminated with arsenic during their pregnancies gave birth to children who manifested changes in their genetic expression such that they were more susceptible to cancer and other diseases...
Gene Linked to E. carotovora Virulence Identified
in The Biotech Weblog, on November 8, 2007
In a study published in the Journal of Bacteriology , scientists have identfieid a gene in the bacterium Erwinia carotovora , that influences its ability to infect and damage crops.
E. carotovora causes blackleg and soft rot in potatoes, but may also infect other crops such as carrots, ...
Genetic Variation Modulate Benefits of Breastfeeding
in The Biotech Weblog, on November 7, 2007
In a recent study published in the Proc. Natl Acad. Sci. , scientists have found out that breastfeeding can indeed boost an infant's brain development and intelligence, provided the baby carried at least one copy of a 'C' allele for a gene called FASD2 , which is involved in the gene...
Multiple Genes Against Turnip Mosaic Virus Identified
in The Biotech Weblog, on November 2, 2007
In a study published recently in the Journal of General Virology , scientists have identified a set of multiple genes in brassicas - broccoli, cabbage, oilseed rape, and the like- that confer resistance to the turnip Mosaic virus (TuMV).
"Turnip mosaic virus can cause big economic l...
Two Genes Linked To Insulin Resistance Identified
in The Biotech Weblog, on October 29, 2007
In a study published recently in the Journal of Biological Chemistry, researchers have identified two genes, NR4A3 and NR4A1 , which seem to boost insulin sensitivity in muscle tissue , and may thus be potential targets for counteracting insulin resistance in Type 2 diabetes patients.
...
Premature Telomere Shortening and Colorectal Cancer
in The Biotech Weblog, on October 28, 2007
Mayo Clinic researchers have identified a genetic abnormality associated with colon cancer (also called colorectal cancer, and includes cancer in the colon, rectum and appendix) in younger individuals, i.e., 50 years old and below.
Dr. Boardman and an interdisciplinary group of researc...
FISH-Based Test Identify Genetic Abnormalities in Plasma Cell Malignancies
in The Biotech Weblog, on October 28, 2007
Mayo Clinic researchers have developed a chromosome FISH-based test which surpasses conventional methods in identifying chromosomal genetic abnormalities associated with plasma cell malignancies and thus help physicians better assess a patient's prognosis and likelihood to respond to a g...
Two Genes Linked to Ankylosing Spondylitis and Graves' Disease
in The Biotech Weblog, on October 23, 2007
Researchers have identified two genes linked to both ankylosing spondylitis , a painful and progressive form of arthritis in which some or all of the spine's vertebrae fuse together, and Graves' disease , an autoimmune condition that causes overactivity of the thyroid gland.
The study ...
Fourth Antibody to Detect Type 1 Diabetes, Discovered
in Daily Diabetic, on October 17, 2007
...disease, a similar approach that is currently used to counter allergies. We also hope that the same genomics-based approach will be applicable to other autoimmune diseases like multiple sclerosis and ...
Novel D-Peptides More Potent Against HIV
in The Biotech Weblog, on October 11, 2007
Scientists at the University of Utah have developed new peptides that appear to be significantly more effective at blocking HIV's entry into cells than other drugs in their class.
"Our 'D-peptides' offer several potential therapeutic advantages over existing peptide entry inhi...
Genetic Profiling Lung Tumors To Determine Best Chemotherapy Options
in The Biotech Weblog, on October 1, 2007
Researchers are exploring the use of genetic profiling in lung tumors to to predict the tumors' likely response to therapy and determine the best treatment strategy for lung cancers.
Researchers looked at the sensitivity of multiple cancerous cell lines to cisplatin, the most commonly used ...
Giardia lamblia Genome Sequenced
in The Biotech Weblog, on September 28, 2007
Scientists have cracked the genetic sequence of Giardia lamblia , a common protozoan parasite causing gardiasis , an intestinal infection considered to be one of the most common causes of waterborne (drinking and recreational) disease. The genome, reported in the recent issue of Science , is e...
Lab-on-a-Chip Device for Detecting Avian Flu
in The Biotech Weblog, on September 25, 2007
Researchers have developed a miniaturized device which can detect the highly pathogenic avian flu (H5N1) virus in throat swab samples, with results released within half an hour.
The device comprises a unique platform that uses magnetic force to manipulate individual droplets containing si...
Computer Program Traces Ancestry Based on DNA Samples
in The Biotech Weblog, on September 23, 2007
Photo: Plot of genetic markers for 255 individuals from four continental regions. Red and green represents identical genotypes. Black represents genotypic variations. Notice the distinct patterns formed in the four continental blocks, highlighting the genetic similarities between people of the ...
Possible Genetic Risk for Fetal Alcohol Disorders, Identified
in The Biotech Weblog, on September 23, 2007
A recent animal study indicates that certain infants and children who carry a certain gene variant may be more vulnerable to fetal alcohol syndrome , a condition characterized by severe mental retardation, with deficits in learning, attention, memory and impulse control. The study's res...
Genetic Basis of Susceptibility to Acute Urinary Track Infections
in The Biotech Weblog, on September 18, 2007
A study published in PLOS ONE reports of a genetic basis for susceptibility to acute pyelonephritis, a severe form of urinary track infection. The IL-8 receptor, CXCR1 , has been identified as a candidate gene in previous animal trials. In human studies, 54% of the APN prone patients had CXCR1...
Green Light for Pharmaceutical Outsourcing in China
in The Outsourcing Weblog, on September 15, 2007
...as leaving them room for further growth and development. Dr Luo Ying, president and CEO of Shanghai Genomics shared the country' main goal stating that "China's goal is not to be a servic...
Gene Controlling Fat Accumulation Identified
in The Biotech Weblog, on September 5, 2007
Researchers have identified a gene in animals called adipose that control whether or not individuals tend to pile on fat, a potential target for fighting obesity and diabetes.
In the current study, the UT Southwestern researchers examined how adipose works by analyzing fruit flies, tiny worms...
Genome Study Reveals Genetic Link to Height
in The Biotech Weblog, on September 3, 2007
By scanning for single nucleotide polymorphisms, or snps, a team of scientists have identified a single-letter difference, either a 'c' or 't', in the <span style=" />HMGA2 gene that accounted for an estimated 0.3% of the height variation in humans.The data is based fro...
Pinot Noir Genome Sequence
in The Biotech Weblog, on August 27, 2007
The French-Italian Public Consortium for Grapevine Genome Characterization has released the grapevine genome sequence of Pinot Noir , a red wine grape variety which lend their flavour to both Burgundy and Champagne wines.
The finished sequence shows a huge expanse of terpene and tannin gen...
Longevity Genes Project Uncover Genetic Components of Aging
in The Biotech Weblog, on August 27, 2007
Comparing DNA samples from 305 Ashkenazi Jews more than 95 years old and a control group of 408 unrelated Ashkenazi Jews participating in Albert Einstein College of Medicine's Longevity Genes Project, researchers determined the prevalence of 66 genetic markers present in 36 genes associated w...
Pepfactant® Switchable Peptide Surfactant
in The Biotech Weblog, on August 22, 2007
(Photo: The tube on the left shows the original emulsion, while the one on the right shows the rapid separation of the emulsion into oil and water after a newly developed "switchable" detergent is added. Credit: Annette dexter , University of Queensland)
Researchers have develop...
Anti-Diabetes Drug Candidate Liraglutide Improves Glucose Control and Lowers Body Weight
in The Biotech Weblog, on August 21, 2007
Two Phase III clinical trials involving more than 2000 patients have shown that Novo Nordisk's new anti-diabetes drug candidate liraglutide have a positive effect on blood glucose control, body weight and hypoglycaemia risks. Liraglutide is a once-daily human analogue of the naturally occurr...
DNA Vaccine Against Multiple Scclerosis Appears Safe
in The Biotech Weblog, on August 15, 2007
Results of a clinical trial funded by Bayhill Therapeutics, Inc. shows that BHT-3009 , a newly developed DNA vaccine against multiple sclerosis appears safe and may produce beneficial changes in the brains and immune systems of individuals with MS. The data is based on a study of 30 patient...
Diabetes Drug Metformin Ma Slow Down Cancer
in The Biotech Weblog, on August 15, 2007
Researchers have discovered that metformin , a commonly prescribed diabetes drug, slows down the growth of cancer cells lacking p53 , a key regulatory gene that regulates Cell division and several metabolic pathways in cells.
The researchers found that metformin instructs cells to sw...
