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20 Cholesterol Regulating Genes Identified
in The Biotech Weblog, on July 8, 2009
© micahb37 Using RNA interference technology, researchers from the European Molecular Biology Laboratory have identified 20 genes involved in cholesterol metabolism , potentially leading to new treatments for heart disease and other cholesterol-related diseases.
Of the 20 genes the scientists...
Azotobacter vinelandii Genome Sequence
in The Biotech Weblog, on June 18, 2009
...has the capacity to maintain low levels of cytoplasmic oxygen through a process called respiratory protection. The sequence of the bacteria's genome allowed the team of researchers to identify the...
Eight Genes That Help Predict Patients Response to Melanoma Treatment
in The Biotech Weblog, on May 31, 2009
A group of researchers have identified eight genes that help predict a melanoma patient's response to treatment .
Dr. Tawbi and his colleagues examined the tumor tissues of 21 patients with metastatic melanoma, some of whom responded to chemotherapy and some who did not. Once the cases wer...
P[acman]-Generated Gene Libraries for Drosophila melanogaster
in The Biotech Weblog, on May 25, 2009
Using a tool called P[acman] , group of researchers has established a library of clones covering most of the genome of Drosophila melanogaster (fruit fly), an organism widely used in genetics research.
P[acman]- developed by Dr. Koen Venken (http://flypush.imgen.bcm.tmc.edu/lab/koenv/index...
Anti-Inflammatory Constituents of Ginseng Identified
in The Biotech Weblog, on May 16, 2009
© centralasian Scientists have identified immunologically active components in ginseng, an herb used in traditional Chinese and other Asian medicine.
Allan Lau led a team of researchers from the University of Hong Kong who identified seven ginseng constituents, ginsenosides , which showed imm...
Lung Cancer Susceptibility Gene Identified
in The Biotech Weblog, on May 2, 2009
Researchers have identified a gene linked to increased lung cancer susceptibility and development . This gene, called RGS17, could result in a genetic predisposition to develop lung cancer particularly in those with a strong family history of the disease.
Using a genetically altered mouse mod...
Google to Invest in Biotechnology
in The Biotech Weblog, on April 2, 2009
...d range of fields, from search and advertising to mobile computing to medical records and personal genomics . Its target is to invest $100 million in the coming year, with the boston area being o...
200,000 Rice Mutants Available for Study
in The Biotech Weblog, on March 6, 2009
Photo courtesy of iStockphoto , Image# 4796039 Scientists are organizing a repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the rice genome. Two hundred thousand rice mutants are now available and have been ...
Genetic Sequencing of Cold Virus
in The Biotech Weblog, on February 19, 2009
Photo courtesy of iStockphoto , Image# 195814 Scientists have successfully mapped the genome of all known human rhinoviruses , which causes the common cold which in turn is responsible for about half of all asthma cases and is a factor in other upper and lower respiratory tract illnesses such a...
Three Genes Linked to Obesity Identified
in The Biotech Weblog, on January 23, 2009
Photo courtesy of iStockphoto , Image# 3457127 Based on a genetic study of 1,380 Europeans, reseachers have identified 3 genes that increase risk of early-onset obesity in children, and morbid obesity in adults .
"The idea was not just to look at run-of-the-mill obesity, but look for gene...
11 New Cardiovascular Risk Gene Variants Identified
in The Biotech Weblog, on December 19, 2008
...sociated with three blood lipids measured to determine cardiovascular disease risk (low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) and triglycerides). These findings were pu...
Brain Enzyme Regulates Appetite and Weight Gain
in The Biotech Weblog, on December 14, 2008
Scientists have determined that an enzyme in the brain called p70 S6 Kinase 1 or S6K may play a role in preventing weight gain and obesity. The researchers injected rats with special viruses that selectively raise or lower S6K activity and found that an increased S6K activity led to reductio...
Genetic Blood Test Provide More Accurate Evaluation For Cystic Fibrosis Patients
in The Biotech Weblog, on December 3, 2008
Photo courtesy of iStockphoto , Image# 2049412 A preliminary "proof-of-principle" trial demonstrated the feasibility of a genetic blood test to demonstrate cystic fibrosis patients' response to therapy.
Using microarray gene analysis of the blood samples, the researchers identifie...
LMID1 Gene Protects Against Lung Cancer
in The Biotech Weblog, on December 3, 2008
...ockphoto , Image# 703709 University of Nottingham researchers have identified a gene that may help protect against lung cancer . By comparing lung cancer tissues from patients with the disease and co...
deCODE BreastCancer Genetic Diagnostic Test Launched
in The Biotech Weblog, on October 13, 2008
Photo courtesy of iStockphoto , Dawn Poland deCoODE Genetics launched deCODE BreastCancer™ , a new non-invasive tool for assessing risk of the common forms of breast cancer.
The deCODE BreastCancer™ test measures seven widely replicated single-letter variations (SNPs) in the human genom...
Non-Invasive Blood Test for Fetal Genetic Anomalies
in The Biotech Weblog, on October 12, 2008
Photo courtesy of iStockphoto , Sylvia Cook Researchers have developed a new prenatal blood test that accurately detected Down syndrome and two other serious chromosomal defects in a small study of 18 pregnant women. The test scan fetal DNA present in the mother's blood to detect chromosom...
GIF1 Gene: Key To High-Yield Rice
in The Biotech Weblog, on September 29, 2008
A gene in rice that controls the size and weight of rice grains has been identified, and may thus be useful for breeding high-yield rice.
"The GIF1 gene is responsible for controlling the activity of the enzyme invertase, which is located in the cell wall and converts sucrose to subs...
Researchers Identify Key Allergy Gene
in Allergies, on August 29, 2008
...in E (IgE) antibodies. IgE antibodies are a particular type of antibody that is normally used to protect against parasites. In Western lifestyle countries with less contact, however, elevated IgE leve...
FRO7 Gene Vital to Photosynthesis and Iron Metabolism in Plants
in The Biotech Weblog, on August 27, 2008
...ast Iron acquisition and is required for efficient photosynthesis. The FRO family is a group of proteins that transfers electrons from ferric iron (Fe3+) to reduce it to another kind of iron (Fe2+...
Kiwi Fruit's Expressed Sequence Tags Published
in The Biotech Weblog, on August 4, 2008
... are likely to have the type of fruit we want."
The genetic data have been published in BMC Genomics .
Source ...
Genetic Sequencing Companies Join 1000 Genomes Project
in The Biotech Weblog, on June 11, 2008
Photo courtesy of iStockphoto, Image# 3676922
Three DNA sequencing companies have joined an international research consortium called 1000 Genomes , aimed at creating a new map of the human genome that will provide a view of biomedically relevant DNA variations at a resolution unmatch...
Genetic Tests to Detect and Predict Recurrence Likelihood of Lung Cancer
in The Biotech Weblog, on May 25, 2008
Two research studies presented during the recently held American Thoracic Society's 2008 International Conference in Toronto point to diagnostic tests for lung cancer: a blood test for accurately detecting lung cancer in its early stages, and a genetic test to predict the likelihood that c...
Use of Genomics to Control Dandruff
in The Biotech Weblog, on May 23, 2008
... The article Dandruff Genomics in a recent issue of The Scientist featured Procter & Gamble scientist Thomas Dawson and the role of genomics in the development of anti- Dandruff shamp...
Gene for Kidney Failure Identified
in The Biotech Weblog, on April 29, 2008
Scientists have identified a gene known as Jund , which controls the activity of a group of cells thought to be responsible for potentially severe inflammation of the kidney. This discovery could offer a route for tackling the auto-immune destruction of kidney tissue which can occur in lupus ...
Flour Beetle Genome Sequence
in The Biotech Weblog, on March 30, 2008
... of about 200 million nucleotides (DNA building blocks) that code for about 16,000 genes (or 16,000 proteins). These sequencing efforts are extremely important for agriculture and will enable the deve...
Gene Plays a Role in Hair Loss Identified
in The Biotech Weblog, on February 27, 2008
...q14.11-13q21.33, and identified homozygous truncating mutations in P2RY5, which encodes an orphan G protein-coupled receptor. Furthermore, we identified oleoyl-L-alpha-lysophosphatidic acid (LPA), a b...
DNA Test for Assessing Prostate Cancer Risks Possible
in The Biotech Weblog, on January 25, 2008
A new genetic test for the early detection or prostate cancer may soon be developed. Until now, a patient's risks of having prostate cancer is based on PSA tests which has a relatively low sensitivity.
Now, however, a research group at Karolinska Institutet and their American colleagues ha...
Preliminary Soybean Genome Released
in The Biotech Weblog, on January 22, 2008
The U.S. Department of Energy Joint Genome Institute (DOE JGI) has released a preliminary assembly and annotation of the soybean genome to the greater scientific community to enable bioenergy research.
The current assembly (representing 7.23x coverage), gene, set, and browser are collec...
Novel Genetic Variants Linked to Heart Disease
in The Biotech Weblog, on January 13, 2008
An international collaboration of scientists have discovered more than 25 genetic variants in 18 genes linked to cholesterol and lipid levels . Such findings may help in estimating an individual's genetic risk of heart disease, as well as lead to a better understanding of cholesterol metabol...
Gefährliche Neujahrsgrüsse: Sexy Girls mit Wurm
in Das CIO Weblog, on December 29, 2007
...fiziert sich dann der Rechner.
Leider erkennt die Anti-Virus und Anti-Trojaner-Software von F-Prot, Kaspersky, McAfee und Sophos bisher den Schädling noch nicht. Also besser die Neugier zähmen und n...
The Human Microbiome Project
in The Biotech Weblog, on December 22, 2007
The National Institutes of Health (NIH) today announced the official launch of the Human Microbiome Project , the collective genomes of all microorganisms present in or on the human body.
Part of the NIH's Roadmap for Medical Research, the Human Microbiome Project will award a total of $1...
Molecular Biology of the Gene, 6th Edition
in The Biotech Weblog, on December 20, 2007
...molecular biology have been included. Two all-new chapters discuss regulatory RNAs (Chapter 18) and genomics and systems biology (Chapter 20). These chapters focus on RNAi and microRNAs, the opportuni...
Toshiba Protégé M700
in The Gadgets Weblog, on December 10, 2007
... There is a lot to like about the Toshiba Protégé m700 .
First of all, it is the first from Toshiba with LED backlighting, as well as an antiglare coating for a terrific indoor and outdoor perf...
Genetic Map for Aging in Mice
in The Biotech Weblog, on November 30, 2007
Using gene arrays, researchers have identified genes whose activity changes with age in 16 different mouse tissues. The study, published in PLoS Genetics , uses a newly available database called AGEMAP to document the process of aging in mice at the molecular level.
As an organism ...
Silk from Bees
in The Biotech Weblog, on November 29, 2007
...ular Biology and Evolution , which discusses the honeybee silk genes and the properties of the coil proteins from the cocoon and nest silks they produce.
"Most people are unaware that bee...
In Utero Arsenic Exposure Leads to Increased Cancer Risk
in Next Nine Months, on November 24, 2007
A recent study published in PLoS Genetics this week indicates that women who whose water supplies were contaminated with arsenic during their pregnancies gave birth to children who manifested changes in their genetic expression such that they were more susceptible to cancer and other diseases...
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in Wangtam, on November 15, 2007
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Gene Linked to E. carotovora Virulence Identified
in The Biotech Weblog, on November 8, 2007
In a study published in the Journal of Bacteriology , scientists have identfieid a gene in the bacterium Erwinia carotovora , that influences its ability to infect and damage crops.
E. carotovora causes blackleg and soft rot in potatoes, but may also infect other crops such as carrots, ...
Genetic Variation Modulate Benefits of Breastfeeding
in The Biotech Weblog, on November 7, 2007
In a recent study published in the Proc. Natl Acad. Sci. , scientists have found out that breastfeeding can indeed boost an infant's brain development and intelligence, provided the baby carried at least one copy of a 'C' allele for a gene called FASD2 , which is involved in the gene...
Multiple Genes Against Turnip Mosaic Virus Identified
in The Biotech Weblog, on November 2, 2007
...ding these genes into commercial varieties of the crop, using conventional techniques, breeders can protect them from attack. But most importantly, we have identified broad-spectrum resistance provide...
Two Genes Linked To Insulin Resistance Identified
in The Biotech Weblog, on October 29, 2007
...or counteracting insulin resistance in Type 2 diabetes patients.
Our findings show that these two proteins help sensitize muscle to insulin, promoting glucose uptake and thus keeping glucose levels ...
Premature Telomere Shortening and Colorectal Cancer
in The Biotech Weblog, on October 28, 2007
...on new treatment strategies such as therapies to reverse premature telomere shortening, stall it or protect the telomeres from destructive influence.
Source: Mayo Clinic ...
FISH-Based Test Identify Genetic Abnormalities in Plasma Cell Malignancies
in The Biotech Weblog, on October 28, 2007
Mayo Clinic researchers have developed a chromosome FISH-based test which surpasses conventional methods in identifying chromosomal genetic abnormalities associated with plasma cell malignancies and thus help physicians better assess a patient's prognosis and likelihood to respond to a g...
Two Genes Linked to Ankylosing Spondylitis and Graves' Disease
in The Biotech Weblog, on October 23, 2007
Researchers have identified two genes linked to both ankylosing spondylitis , a painful and progressive form of arthritis in which some or all of the spine's vertebrae fuse together, and Graves' disease , an autoimmune condition that causes overactivity of the thyroid gland.
The study ...
Fourth Antibody to Detect Type 1 Diabetes, Discovered
in Daily Diabetic, on October 17, 2007
...disease, a similar approach that is currently used to counter allergies. We also hope that the same genomics-based approach will be applicable to other autoimmune diseases like multiple sclerosis and ...
Genetic Profiling Lung Tumors To Determine Best Chemotherapy Options
in The Biotech Weblog, on September 30, 2007
Researchers are exploring the use of genetic profiling in lung tumors to to predict the tumors' likely response to therapy and determine the best treatment strategy for lung cancers.
Researchers looked at the sensitivity of multiple cancerous cell lines to cisplatin, the most commonly used ...
Progranulin Deletion or Mutation Leads to Toxic Proteins Build-up in Neurons
in The Biotech Weblog, on September 28, 2007
...rchers have discovered that a deletion of a gene for progranulin leads to the accumulation of toxic proteins in the brain which subsequently results to dementia.
In the Sept. 26 issue of the Journal ...
Giardia lamblia Genome Sequenced
in The Biotech Weblog, on September 27, 2007
... Scientists have cracked the genetic sequence of Giardia lamblia , a common protozoan parasite causing gardiasis , an intestinal infection considered to be one of the most common causes of waterbo...
Lab-on-a-Chip Device for Detecting Avian Flu
in The Biotech Weblog, on September 25, 2007
Researchers have developed a miniaturized device which can detect the highly pathogenic avian flu (H5N1) virus in throat swab samples, with results released within half an hour.
The device comprises a unique platform that uses magnetic force to manipulate individual droplets containing si...
Protein Biomarkers for Colorectal Cancer Identified
in The Biotech Weblog, on September 24, 2007
... Using two-dimensional gel electrophoresis and mass spectrometry, 27 differentially expressed protein biomarkers for colorectal adenoma have been identified . The differential expression of two of ...
Computer Program Traces Ancestry Based on DNA Samples
in The Biotech Weblog, on September 23, 2007
Photo: Plot of genetic markers for 255 individuals from four continental regions. Red and green represents identical genotypes. Black represents genotypic variations. Notice the distinct patterns formed in the four continental blocks, highlighting the genetic similarities between people of the ...
Possible Genetic Risk for Fetal Alcohol Disorders, Identified
in The Biotech Weblog, on September 23, 2007
A recent animal study indicates that certain infants and children who carry a certain gene variant may be more vulnerable to fetal alcohol syndrome , a condition characterized by severe mental retardation, with deficits in learning, attention, memory and impulse control. The study's res...
Genetic Basis of Susceptibility to Acute Urinary Track Infections
in The Biotech Weblog, on September 18, 2007
... of the APN prone patients had CXCR1 sequence variants. The UTI prone children expressed less CXCR1 protein than the pediatric controls (p<0.0001) and two sequence variants were shown to imp...
Identifying Biological Indicators of Exposure to Cigarette Smoke
in The Biotech Weblog, on September 18, 2007
... indicators of exposure to cigarette smoke. The projects aims to identify a panel of lipid, DNA and protein biomarkers that indicate smoke exposure in smokers' blood, urine, and breath, and to cor...
Green Light for Pharmaceutical Outsourcing in China
in The Outsourcing Weblog, on September 15, 2007
...as leaving them room for further growth and development. Dr Luo Ying, president and CEO of Shanghai Genomics shared the country' main goal stating that "China's goal is not to be a servic...
Gene Controlling Fat Accumulation Identified
in The Biotech Weblog, on September 5, 2007
Researchers have identified a gene in animals called adipose that control whether or not individuals tend to pile on fat, a potential target for fighting obesity and diabetes.
In the current study, the UT Southwestern researchers examined how adipose works by analyzing fruit flies, tiny worms...
Genome Study Reveals Genetic Link to Height
in The Biotech Weblog, on September 3, 2007
By scanning for single nucleotide polymorphisms, or snps, a team of scientists have identified a single-letter difference, either a 'c' or 't', in the <span style=" />HMGA2 gene that accounted for an estimated 0.3% of the height variation in humans.The data is based fro...
Pinot Noir Genome Sequence
in The Biotech Weblog, on August 27, 2007
The French-Italian Public Consortium for Grapevine Genome Characterization has released the grapevine genome sequence of Pinot Noir , a red wine grape variety which lend their flavour to both Burgundy and Champagne wines.
The finished sequence shows a huge expanse of terpene and tannin gen...
Longevity Genes Project Uncover Genetic Components of Aging
in The Biotech Weblog, on August 27, 2007
...st several disease-causing genes, then drugs that mimic the action of the longevity gene could help protect against cardiovascular disease and other age-related diseases.
Source: AECOM ...
DNA Vaccine Against Multiple Scclerosis Appears Safe
in The Biotech Weblog, on August 15, 2007
...f cytokine -producing CD4+ T cells (a type of white blood cell) specifically targeting myelin proteins. This reduction was found in the blood as well as in the cerebrospinal fluid of three patie...
Diabetes Drug Metformin Ma Slow Down Cancer
in The Biotech Weblog, on August 15, 2007
Researchers have discovered that metformin , a commonly prescribed diabetes drug, slows down the growth of cancer cells lacking p53 , a key regulatory gene that regulates Cell division and several metabolic pathways in cells.
The researchers found that metformin instructs cells to sw...
Teneur en protéines des laits infantiles
in Les Boutchous, on June 20, 2007
...er l'influence du lait maternel et de laits infantiles de teneurs différentes en protéines sur les paramètres anthropométriques (poids, taille) et biologiques chez les nourrissons puis les enfants...
New Findings from The Wellcome Trust Case Control Consortium
in The Biotech Weblog, on June 13, 2007
The Wellcome Trust Case Control Consortium has published new findings on the genetics behind common diseases such as diabetes, rheumatoid arthritis and coronary heart disease Nature Genetics .
The £9 million study is one of the UK's largest and most successful academic collaborations to da...
Fifth Gene Responsible for Joubert Syndrome
in The Biotech Weblog, on June 12, 2007
Researchers have identified the fifth gene linked to Joubert syndrome (JS), a rare, genetic disorder that affects the area of the brain that controls balance and coordination, and is thus characterized by ataxia (lack of muscle control), an abnormal breathing pattern called hypernea, sleep ...
13th Gene for Congenital Blindness Identified
in The Biotech Weblog, on June 12, 2007
An internation group of scientists have identified the thirteenth gene to be linked to Leber's congenital amaurosis (LCA), an inherited retinal degenerative disease characterized by severe loss of vision at birth.
The newly-discovered gene, LCA5, is involved in the production of lebercili...
New Genetic Risk Factor for Coeliac Disease Identified
in The Biotech Weblog, on June 11, 2007
...itish, Irish and Dutch populations.
What they found is that healthy individuals more often have a protective DNA sequence in the interleukin-2 and interleukin-21 gene region than individuals with co...
Watson Receives Personal Genome Sequence Data
in The Biotech Weblog, on June 3, 2007
Nobel laureate James Watson - co-discoverer of the DNA double helix and father of the Human Genome Project - became the first human to receive a DVD that contains data on his personal genome sequence, a $1 million, two-month collaborative project of 454 Life Sciences and the BCM Human...
Google Invests $39M in Biotech Start-up on Personal Genetics
in The Biotech Weblog, on May 24, 2007
Google has invested $39 million in 23andme , a privately held, early-stage personal genetics company co-founded by Anne Wojcicki, who is married to Google, Inc. co-founder Sergey Brin.
From the 23andme website:
Even though your body contains trillions of copies of your genome, you've lik...
Mild-persistent Asthma Patients May Switch to Once-daily Flucitasone/Salmeterol
in Straightfromthedoc, on May 24, 2007
...fessor of pediatrics, internal medicine-pulmonary and associate director of the Center for Human Genomics, results of the abovementioned study suggests that patients whose asthma is well controlled on...
New Method for Identifying Marine Microorganisms
in The Biotech Weblog, on May 23, 2007
Researchers from the Bigelow Laboratory for Ocean Sciences report of a new approach in identifying unculturable microorganisms from marine environments .
"We present a novel approach to studying metabolic capabilities of the uncultured microbial taxa. Our method is based on fluorescence...




