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Rho Kinase Inhibitors May Treat Certain Gastrointestinal Disorders
in The Biotech Weblog, on July 19, 2006
An enzyme called Rho kinase has been shown to play a role in maintaining the tone of the internal anal sphincter (IAS). When the IAS tone is too high, the anal sphincter can be hypertensive, and may lead to disorders such as constipation, hemorrhoids, anal fissures , Hirschsprung'...