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Cloning Fosfomycin for More Cost-Effective Production
in The Biotech Weblog, on November 30, 2006
... Fosfomycin is a member of a class of compounds called phosphonic acids, a natural antibiotic approved by the FDA to control pathogens against which penicillin and vancomycin are no longer effective... ...e fosfomycin in Escherichia coli so that they can "use various protein and metabolic engineering tools to manipulate the fosfomycin biosynthetic pathway."
Aside form the success in c...
Fosfomycin Ineffective in Vitro But Shows In Vivo Efficacy Against Listeriosis
in The Biotech Weblog, on May 12, 2006
...is particular paper, the researchers showed that despite it being ineffective in laboratory tests, fosfomycin can actually treat listeriosis , a type of food poisoning caused by the bacterium List... ...ons, the drug candidate does not advance into in vivo trials. A new study published in Nature Medicine , however, indicate that using this screening methodology, we might actually be missing out on c...