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Progranulin Deletion or Mutation Leads to Toxic Proteins Build-up in Neurons
in The Biotech Weblog, on September 28, 2007
...ound that mutation or suppression of progranulin expression leads to an increase in the activity of caspase, which cleave and lead to the accumulation f TDP-43. The speculate that "progranulin co...
Biomarker Test for Bladder Cancer Recurrence and Survival
in The Biotech Weblog, on February 20, 2007
...val of bladder cancer patients. The test is based on the presence of molecular biomarkers Bcl-2 , caspase-3 , P53 and survivin -- proteins known to regulate apoptosis, or programmed cell death.
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Protein Biomarkers Predict Bladder Cancer Recurrence and Survival
in The Biotech Weblog, on February 6, 2007
...iomarkers, are available online in an upcoming issue of The Lancet Oncology .
The proteins Bcl-2, caspase-3, P53 and survivin --proteins known to regulate apoptosis -- were associated with the rate ...
Biosite Inc Obtains Exclusive License for Caspase-1
in The Biotech Weblog, on August 26, 2005
...te Incorporated signed an exclusive license with Johannes Gutenberg University, Mainz, Germany for Caspase-1, a potentially important cardiovascular disease biomarker.
The financial terms of ...