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IVF Success Lies in the Genes
in Next Nine Months, on July 26, 2009
...s predictive of IVF outcome. This finding demonstrates the power of high-dimensional technology in biomarker discovery, and highlights the potential for developing clinically useful tools, they say.
...
Blood Test for Aging Protein p16p16INK4a
in The Biotech Weblog, on June 17, 2009
...s present in cells called T-lymphocytes, also known as T-cells.
They found that expression of the biomarker was strongly correlated with the donor's chronological age and, in fact, increased expo...
Foundation for NIH Facilitated Partnership Announced Availability of Alzheimer’s Genome Biomarker Data
in Straightfromthedoc, on March 20, 2009
... The genome biomarker data for the Alzheimer's Disease Neuroimaging Initiative (ADNI) is ready to be shared with scientists world-wide for further analysis. Such were the announcement of the ...
Pollution-Related Asthma May Start in the Womb
in Allergies, on February 27, 2009
...h confirmation in further studies, researchers say changes in the ACSL3 gene could serve as a novel biomarker for early diagnosis of pollution-related asthma.
If you live in the city, breathing poll...
Biomarkers for Oral Cancer in Saliva
in The Biotech Weblog, on September 30, 2008
... Photo courtesy of iStockphoto , Bradley Mason Researchers have identified five protein biomarkers for oral squamous cell carcinoma , a form of oral cancer,found in the saliva.
Researchers colle...
Protein Biomarkers in Urine for Bovine Spongiform Encephalopathy (BSE)
in The Biotech Weblog, on September 11, 2008
...archers say these findings, published in the journal Proteome Science , may be used to develop a biomarker test for the diagnosis and monitoring of disease progression in BSE and related transmis...
AlloMap®: Novel Non-invasive Test For Managing Heart Transplant Patients
in Straightfromthedoc, on August 27, 2008
...IVDMIA) for use in transplant management.
AlloMap Testing assays the RNA levels of 11 rejection biomarker genes and nine control genes. AlloMap Testing was clinically validated using data from 9 lea...
Using Chicken Antibodies for Detecting HER2 Breast Cancer
in The Biotech Weblog, on February 27, 2008
...quantum dots (tiny, intense and tunable sources of colorful light) to more reliably detect the HER2 biomarker than the existing diagnostic tests using mammalian antibodies tagged with conventional flu...
High Urinary Levels of Certain Molecules: Potential Biomarker of Lupus Nephritis
in Straightfromthedoc, on November 27, 2007
...compounds - VCAM-1, P-selection, TNFR-1 and CXCL 16 - in the urine have the potential to serve as biomarkers for a potentially life-shortening kidney ailment caused by the autoimmune disease lupus ...
Protein Biomarkers for Colorectal Cancer Identified
in The Biotech Weblog, on September 25, 2007
...ing two-dimensional gel electrophoresis and mass spectrometry, 27 differentially expressed protein biomarkers for colorectal adenoma have been identified . The differential expression of two of these...
Identifying Biological Indicators of Exposure to Cigarette Smoke
in The Biotech Weblog, on September 18, 2007
...ors of exposure to cigarette smoke. The projects aims to identify a panel of lipid, DNA and protein biomarkers that indicate smoke exposure in smokers' blood, urine, and breath, and to correlated ...
RBP4: Protein in Blood, Possible Biomarker of Visceral Fat
in The Biotech Weblog, on July 13, 2007
... believe that in the near future, measurements of RBP4 serum concentrations might serve as a novel biomarker for visceral obesity and increased risk for type 2 diabetes and other adverse outcomes of v...
Antibody Developed to Detect Mutant Enzyme Causing Amyotrophic Lateral Sclerosis
in The Biotech Weblog, on May 14, 2007
...ot caused by mutations in SOD1. If this is the case, then the antibody could potentially be used in biomarker studies to facilitate earlier diagnosis of the disease."
The antibody, named SOD1-ex...
Oral Rinse Genetic Test for Head and Neck Cancer
in The Biotech Weblog, on April 23, 2007
...ion and diagnosis of head and neck squamous cell carcinoma (HNSCC). The tes detects CD44, a protein biomarker for HNSCC tumors, and together with the detection of cancer-related altered DNA, could rel...
Bone Drug Risedronate Prevented Hip Fractures in Parkinson's Disease Patients
in Straightfromthedoc, on March 26, 2007
...cent and decreased by nearly three percent in the placebo group.
In addition, researchers found a biomarker for bone loss decreased by nearly 47 percent in the risedronate group and 33 percent in th...
Plant-Derived Omega-3s, Good for Bone Health
in Straightfromthedoc, on February 20, 2007
... oil supplements, this Penn State study is a first of its kind that used whole food sources .
The biomarker for bone resorption - N-telopeptides - decreased significantly during the alpha linolenic ...
Biomarker Test for Bladder Cancer Recurrence and Survival
in The Biotech Weblog, on February 20, 2007
... recurrence and survival of bladder cancer patients. The test is based on the presence of molecular biomarkers Bcl-2 , caspase-3 , P53 and survivin -- proteins known to regulate apoptosis, or pr...
Nestin: A Biomarker for Basal Epithelial Breast Cancer
in The Biotech Weblog, on January 16, 2007
... Last month, we reported on two proteins considered to be biomarkers for breast cancer metastasis onto neighboring lymph nodes. This time, a structural protein called nestin has been linked to th...
Blood Test for NT-proBNP Predicts Cardiac Events and Death in Heart Patients
in The Biotech Weblog, on January 16, 2007
...involving 987 patients with history of cardiovascular disease, those with the highest levels of the biomarker were found to be 3.4 times more likely to die or have a cardiovascular event than patien...
GRK2 Protein: Biomarker for Heart Failure
in The Biotech Weblog, on September 20, 2006
...
Thomas Jefferson University researchers have identified a protein which may be a potential biomarker for heart failure . In a study presented during the 10th Annual Scientific Meeting of the Hea...
Tangled Bank #61 on Epigenetic News
in The Biotech Weblog, on August 31, 2006
...tries which I think would also be of interest to Biotech Weblog readers:
telomere length as a biomarker for aging
genome of a marine bacteria that can degrade petroleum which can be useful ...
High-Sensitivity Blood-Based Detection of Breast Cancer Using Multi Photon Detection Diagnostic Proteomics
in The Biotech Weblog, on August 30, 2006
...ave been found to be potentiated by use of immunoassay panels which include tissue-specific cancer biomarkers as well as cytokines and angiogenic factors . The ultrasensitive immunoassays reveale...
Skin Test for Early Alzheimer's disease, In the Works at BRNI
in Straightfromthedoc, on August 22, 2006
... disease.
The BRNI researchers, in an article entitled: "An Internally Controlled Peripheral Biomarker for Alzheimer's Disease: Erk1 and Erk2 Responses to the inflammatory Signal Bra...
p16INK4a, New Biomarker for Cervical Cancer Screening and Diagnosis
in Straightfromthedoc, on May 18, 2006
...n and Neoplasia (EUROGIN) in Paris, mtm Laboratories AG announced the potential of p16INK4a as biomarker for cervical cancer screening and diagnosis.
Several studies presented at the meeting ev...
Protein Biomarkers Predict Status of Kidney Transplants in Patients
in Straightfromthedoc, on April 27, 2006
... Using protein biomarkers called NGAL and IL-18 in kidney transplant patients will determine whether these patients will require dialysis within the first week of transplant surgery. A study cit...
Nanogen Inc. Granted Two New Patents on Proteomics and Diagnostics
in The Biotech Weblog, on April 18, 2006
...ts to Nanogen, Inc. , developer of advanced diagnostic products, for inventions related to disease biomarkers:
1) U.S. Patent No. 7,014,854:"Method for Retarding or Precluding Alzheimer's...
blood test for early detection of breast cancer, enters phase 2 clinical trial
in Straightfromthedoc, on March 6, 2006
...The launch of a clinical study for its revolutionary blood test for breast cancer was announced by Biomarker Technologies , a Phoenix-based company. The test has shown significant accuracy that excee...
Hand-Held Device For Screening Diseases
in The Biotech Weblog, on February 16, 2006
...hemical sensors "trained" to recognize complex chemical patterns, some of which are known biomarkers for certain Diseases .
According to the principal investigator, Frank V. Bright: T...
Ribomed Biotech Granted $3.5M Anti-Terrorism Contract
in The Biotech Weblog, on February 14, 2006
...gens in food
a portable biowarfare detector called Handheld Isothermal Silver Standard Sensor
a biomarker-based device to detect early stage-cancer
As prime Contractor for the Homeland ...
Bio-Partnering on the Horizon in China
in China Venture News, on December 13, 2005
...nces Group, Deloitte, Amgen, Roche, Eli Lilly, GSK, Pfizer, Perkins Coie, Heller Ehrman, Epitomics, BioMarker, excel and Baxter are also scheduled to speak at the forums.
"This event is t...
BioVisioN AG and Abbott Sign Research Agreement
in The Biotech Weblog, on September 13, 2005
...igned an agreement with Abbott to collaborate on research relating to the discovery of novel biomarkers for lung cancer. According to the agreement, BioVisioN will be paid to analyze biological...
Biosite Inc Obtains Exclusive License for Caspase-1
in The Biotech Weblog, on August 26, 2005
...erg University, Mainz, Germany for Caspase-1, a potentially important cardiovascular disease biomarker.
The financial terms of the agreement were not disclosed.
Read press release here ....
Peakadilly Receives Patents for Protein Biomarker Discovery Technologies
in The Biotech Weblog, on August 19, 2005
...cal sample and represents the most important component of the company's MASStermind� biomarker discovery engine.
"We are extremely pleased with the decisions of the US, Canadian and Eu...