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200,000 Rice Mutants Available for Study
in The Biotech Weblog, on March 6, 2009
Photo courtesy of iStockphoto , Image# 4796039 Scientists are organizing a repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the rice genome. Two hundred thousand rice mutants are now available and have been ...
Use of Genomics to Control Dandruff
in The Biotech Weblog, on May 23, 2008
...ontracting with Integrated Genomics in Chicago to sequence the entire genome of M. globosa. P&G bioinformatics expert Jun Xu's analysis revealed that the M. globosa genome was tiny, consisting...
Natural Products Discovery and Production
in The Biotech Weblog, on February 25, 2008
...throughput screening, genome shuffling, defined media, novel instrumentation, bioreactor operation, bioinformatics, etc., will be discussed within the context of key cultures.
Developments will be ex...
World's Biggest Mathematical Simulation of the Heart
in The Biotech Weblog, on January 20, 2008
... Using bioinformatics and supercomputers , University of Montreal researchers were able to create the largest-ever mathematical simulation of the electrical activity of a human heart - a 2 bil...
The Human Microbiome Project
in The Biotech Weblog, on December 22, 2007
The National Institutes of Health (NIH) today announced the official launch of the Human Microbiome Project , the collective genomes of all microorganisms present in or on the human body.
Part of the NIH's Roadmap for Medical Research, the Human Microbiome Project will award a total of $1...
Lab-on-a-Chip Device for Detecting Avian Flu
in The Biotech Weblog, on September 25, 2007
Researchers have developed a miniaturized device which can detect the highly pathogenic avian flu (H5N1) virus in throat swab samples, with results released within half an hour.
The device comprises a unique platform that uses magnetic force to manipulate individual droplets containing si...
ACuRay™ Acoustic Sensor for Cancer
in The Biotech Weblog, on September 21, 2007
Researchers from the Georgia Institute of Technology have created ACuRay ™ (stands for standing for ACoustic micro-arRay), an acoustic sensor that can detect small amounts of mesothelin , a molecule associated with a number of cancers including mesothelioma. The device consists of an array of e...
Identifying Biological Indicators of Exposure to Cigarette Smoke
in The Biotech Weblog, on September 18, 2007
The National Institutes of Health's new Genes, Environment, and Health Initiative (GEI) has awarded the Center of Excellence in Environmental Toxicology (CEET) at the University of Pennsylvania School of Medicine a grant of $2.3 million over the next four years to study biological indicators ...
Google Invests $39M in Biotech Start-up on Personal Genetics
in The Biotech Weblog, on May 24, 2007
Google has invested $39 million in 23andme , a privately held, early-stage personal genetics company co-founded by Anne Wojcicki, who is married to Google, Inc. co-founder Sergey Brin.
From the 23andme website:
Even though your body contains trillions of copies of your genome, you've lik...
New Method for Identifying Marine Microorganisms
in The Biotech Weblog, on May 23, 2007
Researchers from the Bigelow Laboratory for Ocean Sciences report of a new approach in identifying unculturable microorganisms from marine environments .
"We present a novel approach to studying metabolic capabilities of the uncultured microbial taxa. Our method is based on fluorescence...
Proline Dehydrogenase Model Reveals Role in Apoptosis
in The Biotech Weblog, on May 13, 2007
In order to elucidate its function in apoptosis, researchers have created a model of proline dehydrogenase , an important cancer-preventing enzyme in the human body. Proline dehydrogenase enables the creation of superoxide, a highly reactive electron-rich oxygen species involved in the destruct...
Saving Science From Itself
in Philoneist, on April 10, 2007
...now the difference between biochemistry, geochemistry, biogeochemistry and paleobiogeochemistry and bioinformatics. But for your average professional who itches his or her scalp in curiosity while rea...
Metabolomics and Nutrigenomics Symposium
in The Biotech Weblog, on March 6, 2007
...t -gene interactions, the use of metabolomics and nutrigenomics as clinical tools, and how bioinformatics can facilitate new discoveries. Approximately 300 researchers in the field are expec...
Phorecaster: Forecasting Tool Could Reduce Drug Development Costs
in The Biotech Weblog, on February 14, 2007
A teams of researchers from the Children's Hospital Boston Informatics Program (CHIP) has developed a forecasting model called Phorecaster , to predict the probability that a given new drug would pass successfully through Phase III trials and receive New Drug Application (NDA) approval.Th...
The Diabetes Genetics Initiative
in The Biotech Weblog, on February 13, 2007
The Broad Institute, Lund University and Novartis have announced the completion of a genome-wide map of genes related to type 2 diabetes and other metabolic disorders.
Driven by recent advances in the knowledge of human genetic variation, high-throughput genomic technologies, and computa...
Using Preteomic Profiling to Predict Premature Birth
in The Biotech Weblog, on February 12, 2007
Scientists have identified a proteomics-based method to predict the risks of pre-term childbirth due to amniotic fluid inflammation. A profile based on the presence of human neutrophil defensin 1, human neutrophil defensin 2, calgranulin C and calgranulin A make up an MR score.
The research tea...
Horse Genome Sequence Database Now Publicly Accessible
in The Biotech Weblog, on February 12, 2007
The first draft of the horse genome sequence is now publicly available for use by biomedical and veterinary researchers around the globe.
In addition to sequencing the horse genome, researchers produced a map of horse genetic variation using DNA samples from a variety of modern and ancestral...
Improving Crop Plants Through Genomics
in The Biotech Weblog, on January 30, 2007
Current research on the genetic improvement of crops have been highlighted in the January 2007 issue of Agricultural Research magazine . PSNL scientists are applying genomics and related sciences such as proteomics and computational biology to improve the nutritional value of leading cr...
In Silico Screening of Chinese Herbs Using Random Forest
in The Biotech Weblog, on January 25, 2007
Researchers from the King's College London have conducted the first large-scale computer screenings of chinese herbs , which revealed a wide variety of compounds with potential for use in treating HIV/AIDS, cancer, Alzheimer's Disease, arthritis and other diseases. They used Random...
GreeneChip DNA Chip for Detection of Pathogens
in The Biotech Weblog, on December 7, 2006
Scientists have developed a new diagnostic device that can potentially identify thousands of different pathogens from human samples.
Called the "GreeneChip," this device consists of a glass slide onto which are attached nearly 30,000 pieces of genetic material taken from thousands of ...
Three Protein Biomarkers Predict Chronic Lung Transplant Rejection
in The Biotech Weblog, on November 3, 2006
Three proteins that could predict chronic lung transplant rejection up to 20 months before clinical manifestations of rejection becomes apparent, have been identified. Mass spectrometry and bioinfomatics confirmed previous findings that the levels of human neutrophil peptide (HNP) was t...
Two-Component Lantibiotic Haloduracin From Bacillus halodurans
in The Biotech Weblog, on November 1, 2006
...slationally modified to an active form, and act in synergy to provide antibacterial activity. Using bioinformatics, the researchers used genes from the gram -positive bacterium Bacillus halodur...
Mouse Resequencing and SNP Discovery Project Completed
in The Biotech Weblog, on October 26, 2006
A recently completed DNA sequencing of the 15 mouse strains most commonly used in biomedical research showed that there were more than 8.3 million single nucleotide polymorphisms (SNPs) in their genomes. These data will help researchers understand and possibly identify potential therapeutic ...
Entelos Collaborates With Novartis On In Silico Drug Trials
in The Biotech Weblog, on August 23, 2006
Before drugs make it to the commercial production, they are first tested in vitro i.e., under laboratory conditions. And then they go through in vivo , or clinical trials involving animal and ultimately, human models. But in between these two stages, did you know that there is also an optional...
ENDEAVOUR: Computer Program For Identifying Disease Genes
in The Biotech Weblog, on May 10, 2006
Researchers from ESAT-SCD (Engineering Sciences) and the Flanders Interuniversity Institute for Biotechnology (VIB) have developed ENDEAVOUR , a computer program that compiles and processes data from a variety of databases and identifies the genes that play a key role in a particular geneti...
Booming Biotech Industry in the Asia Pacific
in The Biotech Weblog, on April 12, 2006
...oised to become the major hub in producing generic biopharmaceutical drugs, stem cell research, and bioinformatics and clinical data management. Just recently, India announced plans to build 10 new b...
VBI Database For Oomycetes and Microbial Genomes Launched
in The Biotech Weblog, on March 9, 2006
...
The Virginia Bioinformatics Insitute (VBI) launched a free microbial database of microbial genome sequences, particularly of plant pathogens such as Phytophthora sojae and Phytophthora ramorum...
Nutrigenomics: Science Fact or Fiction?
in The Biotech Weblog, on March 4, 2006
...dy to fully exploit the possibilities of this new science. Experts are convinced that more powerful bioinformatics and chemometrics need to be developed to cope with the ever increasing mountain of da...
Developing Better Gadgets For Biometric Identification And Authentication
in The Biotech Weblog, on February 23, 2006
This entry is submitted by Gloria Gamat, via Creative Reporter . In this day and age, if there is a hot buzzword in identity management and protection from terrorists and identity thieves that isn't foolproof: it's called biometrics .
According to Anil Jain, a University Di...
SENSEMAKER: Biology Inspired Machines With Artificial Intelligence
in The Biotech Weblog, on February 16, 2006
This entry is submitted by Gloria Gamat, via Creative Reporter . Computer Science's most intractable problem is teaching a machine to sense its environment. However, a European project is now looking at nature to take up that challenge by combining streams of sensory data to produ...
Sens-it-iv: Bioinformatic Simulation to Evaluate Potential Allergens
in The Biotech Weblog, on February 8, 2006
This entry is submitted by Gloria Gamat, via Creative Reporter . The most reliable way of testing the allergenic potential of a chemical substance is through animal experimentation. However, the European Union wishes to gradually reduce the number of animals used in toxicity tests.
Sens-it...
New Genomic Method Enables Gene Disruption in Pathogenic Fungi
in The Biotech Weblog, on February 3, 2006
... on a genome-wide scale in this fungal pathogen has been developed by Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech, Colorado State University, and Duke University Medi...
Novel Biometrics Technology Yields Human Bar Code Based From Vein Maps
in The Biotech Weblog, on February 2, 2006
This entry is submitted by Gloria Gamat, via Creative Reporter . Luminetx , a small medical supply company in Memphis, Tenn., has developed a new method of palm-reading : a technology based on an infrared scan of the blood cells running through veins, which is then analyzed by a computer...
The Crops Research Informatics Lab (CRIL) Launched
in The Biotech Weblog, on January 28, 2006
This entry is submitted by Gloria Gamat, via Creative Reporter . Monday, 23rd January, marked the launch of The Crops Research Informatics Lab (CRIL) , the first tangible product of an initiative that's probably considered the biggest alliance in the world of Agricultural Research: The ...
US DA and DOE To Sequence Soybean DNA
in The Biotech Weblog, on January 18, 2006
The US Departments of Agriculture and Energy will collaborate to study plant and microbial genomics.
"Both agencies will leverage their expertise and synergize activities involving agricultural- and energy-related plants and microbes," said Dr. Ari Patrinos, Department of Energy Assoc...
BASF Plant Science Obtains Exclusive Licence Rights to Genetically Improved Crops From CropDesign
in The Biotech Weblog, on December 19, 2005
...Biotechnology, belgium -based CropDesign uses its proprietary TraitMill platform--proprietary bioinformatics tools, high throughput gene engineering systems, efficient methods for plant transfor...
IUPHAR Receptor Database Launched
in The Biotech Weblog, on December 5, 2005
The International Union of Basic and Clinical Pharmacology (IUPHAR) launched the IUPHAR Receptor Database , a collection of information on G Protein-coupled receptors (GPCRs) , which is one of the most common target molecules in drug development.
The goal of the IUPHAR database is to provide...
Patenting Human Genes
in The Biotech Weblog, on October 17, 2005
A recent acticle in Science (subscription required) estimates the number of patented humand genes at around 4,382, of the total of 23,688 human genes identified so far. According to the Personal Genome blog ,
"While most patented genes have only one IP claim on them, some genes ...
Bio Hyakka: A Bio Reagent Search Site
in The Biotech Weblog, on September 11, 2005
INTEC Web and genome Informatics (W&G) announced las week that it has opened Bio Hyakka , a website for searching information on reagents for biological researches, currently on beta. The site accepts search words in either Japanese or English, and the search service is free.
Automated DNA Sequencer, BLAST and Bioinformatics
in The Biotech Weblog, on August 31, 2005
...database at GenBank runs on.
As alison Cook put it:
Where would the Human Genome Project, bioinformatics, and life sciences in general, be without (them)? ...
Free Access to 100 Gigabases of DNA & RNA Sequences
in The Biotech Weblog, on August 24, 2005
...on -- GenBank (Bethesda, Maryland USA), European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-Bank in Hinxton, UK), and the DNA Data Bank of Japan (Mishima, Japan...
The -Omics Series, Part 1: Genomics
in The Biotech Weblog, on August 12, 2005
...
This is the first of a series of posts I'm planning to do covering the different -omics. As bioinformatics-aided technologies continue to emerge, it's getting harder and harder to keep up ...
Microbia Collaborates with A*Star
in The Biotech Weblog, on July 26, 2005
Image: Precision Engineering
by Microbia Secondary metabolites produced from fermentation of actinomycetes are one of the most important sources of pharmaceuticals. Microbia, Inc. announced yesterday that its Precision Engineering business unit has entered into a research collaboration ...
21 companies to watch
in TJ's Weblog, on October 19, 2004
Red Herring selects 21 companies that have a good chance to make it big. Good summaries...




