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Victoza® (liraglutide) Received EU Marketing Authorization
in Daily Diabetic, on July 6, 2009
...received narketing authorization by the EU.
Victoza is the first once-daily human glucagon-like peptide-1 (GLP-1) analog developed for the treatment of type 2 diabetes and is now authorized in all ...
Diabetes Drug Januvia May Trigger Pancreatitis, Pancreatic Cancer
in Daily Diabetic, on April 30, 2009
...a member of a new class of drugs that enhance the actions of the gut hormone known as glucagon-like peptide 1 (GLP-1), which has been shown to be effective in lowering blood sugar in people with type ...
Stem Cell Transplantation Benefits Type 1 Diabetics
in Daily Diabetic, on April 14, 2009
...tion and function and chronic complications of type 1 diabetes mellitus (DM), and the higher the C-peptide levels (a byproduct of insulin production, made up of amino acids), the lower the incidence o...
Cinnamon May Improve Blood Sugar Levels
in Daily Diabetic, on February 21, 2009
...sulin levels, the hormone responsible for controlling blood sugar levels, and increased levels of a peptide reported to work by delaying the emptying of the stomach (gastric emptying).
Despite the in...
Stress During Childhood Linked to Increased Allergy Risks
in Allergies, on September 2, 2008
...rgies.
Blood samples from 234 children showed increased blood concentrations of the stress-related peptide VIP (vasoactive intestinal polypeptide) as well as an increased concentration of immune mark...
Fighting Cancer with Magnetic Nanoparticles
in Nanotechbuzz, on July 21, 2008
...mbination of the two. The researchers at Georgia Tech are also working with other groups to see how peptide-directed gold nanoparticles and nanohydrogels might also be used to combat cancer. Source: ...
Diet and Type 2 Diabetes
in Daily Diabetic, on July 15, 2008
...o significant reductions in many diabetes related factors, such as insulin resistance, fasting C-peptide , fasting proinsulin, fasting blood glucose, fasting triglycerides, and fasting cholester...
Cancer Detecting Nanoparticles
in The Biotech Weblog, on May 30, 2008
... Scientists have designed peptide-coated iron oxide nanoparticles that can seek out tumor cells and make detection using magnetic resonance imaging possible.
The team created peptide-coated iron...
Secretions of South American Frog: New Hope for Diabetes Treatment?
in Daily Diabetic, on March 6, 2008
... vital hormone which is deficient in diabetes sufferers.
Scientists made an artificial copy of the peptide, or protein building block, and showed that it could be used to boost insulin production ...
(Pro3)GIP Injections May reverse Obesity and Diabetes
in The Biotech Weblog, on January 6, 2008
... Scientists have identified a gastric inhibitory polypeptide (GIP) receptor antagonist called (Pro3)GIP , which has been demonstrated in an animal model to be capable of promoting weight loss, imp...
Hormone Blocker Found May Prevent Obesity and Diabetes
in Daily Diabetic, on January 4, 2008
...The hormone called gastric inhibitory polypeptide (GIP) receptor blockade has been found capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model.
...
Peptide Drug Aimed at Two Bioterror Agents
in The Biotech Weblog, on December 21, 2007
... a drug candidate against potential bioterror agents, Hendra and Nipah viruses. The compound is a peptide (protein) related to a parainfluenza virus that appeared to block "pseudo" He...
Progression of Parkinson's Disease May Be Prevented by Peptide Therapy
in Straightfromthedoc, on November 25, 2007
...A peptide that can reverse the biochemical, cellular and anatomical changes that occur in the brains of mice with Parkinson's disease (PD) has been successfully used in preventing the dis...
Peptide Therapeutics Symposium
in The Biotech Weblog, on November 5, 2007
... What : San Diego's 2nd Annual peptide Therapeutics Symposium
When : November 10, 2007
Where : The Hilton, La Jolla Torrey Pines, CA
Internationally acclaimed speakers from will prov...
Diabetes Drug Diamyd™ Passed Phase II of Type 1 Diabetes Trial
in Daily Diabetic, on October 30, 2007
...ived Diamyd™ produced approximately twice as much meal stimulated insulin (as measured by C-peptide ) 15 months after the first treatment as compared to the placebo group (p ~ 0.01). Preserving ...
Novel D-Peptides More Potent Against HIV
in The Biotech Weblog, on October 11, 2007
... Scientists at the University of Utah have developed new peptides that appear to be significantly more effective at blocking HIV's entry into cells than other drugs in their class.
"Our ...
Exenatide, Better than Insulin Glargine
in Daily Diabetic, on September 22, 2007
...owed significant improvements in beta-cell function as measured by arginine and glucose induced C-peptide (a peptide associated with insulin production) secretion during a glucose clamp procedu...
The Gut has Glucose Receptors Too
in Daily Diabetic, on September 4, 2007
...transporter 1 and Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1 .]...
Pepfactant® Switchable Peptide Surfactant
in The Biotech Weblog, on August 22, 2007
...ensland)
Researchers have developed Pepfactant® , a biological detergent or surfactant made from peptides which can be "switched on" or "switched off" depending on its intended a...
Anti-Diabetes Drug Candidate Liraglutide Improves Glucose Control and Lowers Body Weight
in The Biotech Weblog, on August 21, 2007
... Liraglutide is a once-daily human analogue of the naturally occurring hormone glucagon -Like Peptide-1 (GLP-1), and works by stimulating the release of insulin only when glucose levels become t...
Rheuma und Arthritis, Gelenkentzuendung: neuer Test, Diagnose beim Hausarzt einfacher
in Das Gesundheits-Weblog, on July 9, 2007
...ibt einen sehr speziellen "Marker": Antikörper gegen CCP (sog. zyklische citrullierte Peptide). In dem Labortest, der von den gesetzlichen Kassen bezahlt wird, werden beide Marker bestimmt: ...
BYETTA® Can Sustain Blood Glucose Control in Type 2 Diabetics
in Daily Diabetic, on July 2, 2007
...es. BYETTA® exhibits many of the same effects as the human incretin hormone glucagon like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through multiple effects that work in c...
Natürlicher HIV-Hemmstoff entdeckt: neue Klasse von AIDS-Medikamenten ?
in Das Gesundheits-Weblog, on June 27, 2007
...rt. Weiterhin fanden sie, dass einige wenige Aminosäureaustausche in der Sequenz dieses Peptides, als VIRIP (VIRus-Inhibitorisches-Peptid) bezeichnet, die Wirksamkeit gegen HIV-1 um etwa das 100-fache...
Liraglutide: Novo Nordisk Diabetes Drug, Better Than Insulin Therapy?
in Daily Diabetic, on June 21, 2007
...ulin glargine.
A once-daily human analogue of the naturally occurring hormone glucagon -Like Peptide-1 (GLP-1), liraglutide works by stimulating the release of insulin only when glucose level...
How Gastric Bypass Surgery Gets Rid of Diabetes: Welsh Medics Will Take a Look
in Daily Diabetic, on June 4, 2007
...ogether with Dr Jeffrey Stephens are focusing attention on a protein known as glucagon Like Peptide 1 (GLP-1) - a protein produced in the small intestine.
Find more details from the full repo...
Naturally Occurring Peptide in Human Blood Can Block HIV
in Straightfromthedoc, on April 24, 2007
...e been able to identify a relatively abundant molecule in the human blood -called VIRUS-INHIBITORY PEPTIDE or VIRIP - which has been found to be effective in blocking HIV-1.
Moreover, they showe...
RAMP1: The Protein that Promotes Migraine
in Straightfromthedoc, on March 12, 2007
...is protein seem to "turn up the volume" of a nerve cell receptor's response to a neuropeptide - called CGRP (calcitonin gene-related peptide) - that can cause migraines, which probably e...
Natural Fibre Oligo Fructose: Promising New Diet Product on Human Trial
in Straightfromthedoc, on February 6, 2007
...vious study with rats that the fiber increases the levels of a satiety hormone called glucagon-like peptide (GLP-1) in the body and increases a gene in the intestines that helps the body to create mor...
Peptide Vaccine with Toll-Like Receptor Agonists Against Breast Cancer
in The Biotech Weblog, on February 5, 2007
... In mouse trials, scientists have demonstrated the efficacy of a peptide vaccine against breast cancer. The vaccine includes toll-like receptor agonists as well as antibodies to blunt other aspects ...
Blocking Apo E and Amyloid Beta Interaction to Target Alzheimer's Disease
in Straightfromthedoc, on December 23, 2006
...logy, Pathology and Psychiatry, the research team created a nontoxic, synthetic protein fragment or peptide that binds to apo E, preventing it from latching onto amyloid. Once deprived of its biochemi...
Biomarkers for Breast Cancer Metastasis
in The Biotech Weblog, on December 18, 2006
...ted . Although yet unidentified, scientists speculate that these proteins are thymosin beta-10 , a peptide that has already been associated with out-of-control growth and cell differentiation, and a...
Yeast Model As Tool For Alzheimer's Disease Drug Discovery
in The Biotech Weblog, on November 29, 2006
...mation can be detected," said Liebman. "The system employs a fusion of the human A-beta peptide to a functional yeast protein, called a reporter protein, which is only active in allow...
OLAY 新生全新包装升级版
in IN 女人, on November 18, 2006
在杂志上看到 OLAY 新生系列的广告包装与之前不同，感觉新包装超华丽，大约是为了即将来的圣诞节作准备吧。但是价格好像也有略为上升的样子。各大商家都已经纷纷有了举措。呼，期待着大降价。
$1 Million Grant to Develop Topical Cream Against UV Damage
in The Biotech Weblog, on November 6, 2006
...rated that alpha-MSH can repair UV damage to the skin. current research also involves modifying the peptide of 13 amino acids to a chain of only four amino acids, or shorter, to make it more effective...
Three Protein Biomarkers Predict Chronic Lung Transplant Rejection
in The Biotech Weblog, on November 3, 2006
...s spectrometry and bioinfomatics confirmed previous findings that the levels of human neutrophil peptide (HNP) was three times more likely to be elevated among those who later suffered chroni...
Engineered Heparans: New Treatments for Alzheimer's disease, under Development
in Straightfromthedoc, on November 1, 2006
...n. These clumps are clumps are formed from a small protein fragment called Amyloid-beta (A-beta) peptide released from its 'parent' protein - amyloid precursor protein (APP) - a proce...
Aminopeptide: neues Bluff-Wort in der Kosmetik
in Das Gesundheits-Weblog, on November 1, 2006
...gern bei Plazeboalarm ...
Ein neues "Zauberwort" in der Kosmetik heißt "Aminopeptide", z.B. hier . Nur ein Bluffwort, wie plazeboalarm nachgewiesen hat.
"Hauptbelastungs...
EliA™ CCP: New Diagnostic Test that Detects Rheumatoid Arthritis (RA) in Early Stages, Received USFDA Clearance
in Straightfromthedoc, on October 29, 2006
...S Inc. , is the first and only fully automated assay for the measurement of cyclic citrullinated peptide (CCP) antibodies --a highly specific indicator for rheumatoid arthritis (RA) that is found in...
Nano-liquid stops bleeding in seconds
in Nanotechbuzz, on October 12, 2006
...e new material is formulated at the nanoscale from individual amino acids to form a self-assembling peptide. On contact with tissue, the amino acids form a network of fibers that stop the bleeding.
...
Peptide Solution Halts Bleeding
in The Biotech Weblog, on October 11, 2006
...
Researchers from MIT and Hong Kong University have discovered a peptide-containing solution that can be used to stop bleeding immediately i.e., less than 15 seconds. Although the exact mechanism o...
Diabetes Drug To Be Tested As Diet Drug
in Daily Diabetic, on September 19, 2006
... who are not diabetics.
Liraglutide, a long-acting derivative of the natural hormone glucagon-like peptide-1 (GLP-1), in phase II trials improved the ability of pancreatic beta cells to secrete insul...
Snail Toxin For Developing Drugs Against Neurological Disorders
in The Biotech Weblog, on August 21, 2006
... Scientists have been able to isolate a "conotoxin", a peptide from the venomous Cone snail Conus omaria (photo) that seems to block the nicotine receptors in the brain. While the...
BNP Hormone Detects Pulmonary Hypertension in Sickle Cell Patients
in The Biotech Weblog, on July 21, 2006
...
Scientists have identified a hormone, called brain natriuretic peptide or BNP , that can identify patients with sickle cell disease whose condition have progressed to pulmonary hypertension . ...
Cardeva™ for Chronic Heart Failure (CHF), Clinical Trial On-going
in Straightfromthedoc, on July 20, 2006
... Cardeva™ is CoGenesys, Inc. 's long-acting form of b-type natriuretic peptide (BNP) which last week has been granted USFDA approval to commence clinical trial in the United States.
Carde...
Rapamycin May Protect Heart Against Tissue Damage
in The Biotech Weblog, on July 7, 2006
...
Rapamycin (also called sirolimus , marketed as Rapamune® by Wyeth) is a peptide produced by Streptomyces hygroscopicus , originally developed as an antibiotic, but is more commonly used as a...
Novel Peptide for Imaging and Drug Delivery Tool for Lymphoid Cancers
in The Biotech Weblog, on June 15, 2006
...Scientists have developed a peptide that, like monoclonal antibodies, can bind to the surface of leukemia and lymphoma cells. Unlike monoclonal antibodies, however, they are
(1) smaller, and c...
Nastech To Start Human Clinical Trials on Intranasal Obesity Spray
in The Biotech Weblog, on June 7, 2006
...t obesity , and upon approval, hopes to then initiate human clinical trials.
How does PYY work?
Peptide YY is a naturally occurring hormone that is believed to function as a physiologic inhibit...
Novel Combinatorial Therapy Against Type-1 Diabetes
in The Biotech Weblog, on April 24, 2006
...llergy & Immunology studied the effect of a combination of anti-CD3 antibody and proinsulin peptide as therapy against Type-1 diabetes and found that in mice, the combination more efficient l...
Can A Drug Cocktail Reverse Type 1 Diabetes?
in Daily Diabetic, on April 21, 2006
...wo drugs that when ingested, can reverse Type 1 diabetes. The drugs are a monoclonal antibody and a peptide that have been moderately successful when used alone, but when combined, seemed to promise a...
PNA FISH Culture Identification Kits: Saves Hospitals in Anti-Fungal Expenditures
in The Biotech Weblog, on April 18, 2006
...t-positive blood culture.
PNA FISH is a novel Fluorescence In Situ Hybridization concept using Peptide Nucleic Acid probes targeting species-specific rRNA sequences. AdvanDx, Inc. , the maker of...
possible universal strategy to stop drug addiction
in Straightfromthedoc, on February 15, 2006
...ocess sparked by drugs of abuse.
Armed with this knowledge, the team designed a molecule called a peptide, tailored to fit the serotonin receptors and block PTEN. When rats were treated with this PT...
Antimicrobial Peptide From American Oyster
in The Biotech Weblog, on December 1, 2005
...
It seems like the sea is proving to be a mine for anitmicrobial peptides (see previous entries on compounds from Fijian seaweeds and furanones ). This time, researchers from the North Carolin...
Plectasin: Novel Antimicrobial Peptide
in The Biotech Weblog, on October 12, 2005
...
Alas, after more than 3 decades of research on antimicrobial peptides, UCLA professor Robert Lehrer, M.D. and his team identify an antibiotic that promises to be at least as effective as penicilli...
BioVisioN AG and Abbott Sign Research Agreement
in The Biotech Weblog, on September 13, 2005
...tivities in the area of proteomics and peptidomics are now paying off. We are the world leader in peptide biomarker discovery with our patent protected technologies. We are proud that Abbott has cho...
Nerve and Brain Cell Damage Reversal
in The Biotech Weblog, on July 28, 2005
...ed yesterday in the Journal of Neuroscience Research , however, shows how a protein called KDI tri-peptide (KDI) can block the harmful effects of glutamate and allow nerve cells to regenerate.
When ...
Procyon Acquires Bioxalis Medica Inc.
in The Biotech Weblog, on July 13, 2005
...osome drug carriers containing Dovorubicin, a cytotoxic drug, combined with a targeting device (NGR peptide). The targeting device specifically identifies a receptor (CD13 isoform) found only in the v...